The Effect of Plant Sterol Supplement on Blood Cholesterol

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00485095
Recruitment Status : Completed
First Posted : June 12, 2007
Last Update Posted : July 1, 2011
Mills DA
Information provided by:
Oslo University Hospital

Brief Summary:
The purpose of this study is to determine whether supplement of plant sterol could lower blood cholesterol.

Condition or disease Intervention/treatment Phase
High Blood Cholesterol Level Behavioral: Intake of plant sterols Phase 4

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 41 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Double (Participant, Care Provider)
Primary Purpose: Treatment
Official Title: A Single Centre, Randomized Crossover Double-Blind Placebo-Controlled Study to Measure the Effect of Plant Sterol Supplement on Blood Cholesterol
Study Start Date : January 2007
Actual Primary Completion Date : July 2007
Actual Study Completion Date : July 2007

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Ages Eligible for Study:   18 Years to 80 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Men and women 18-80 years old
  • Total cholesterol: 4.5-7.5 mmol/l
  • Triglycerides at or below 4.0 mmol/l

Exclusion Criteria:

  • BMI at or above 35 kg/m2
  • Secondary hyperlipidemia, included diabetes
  • Hypertension (at og higher than 170/110)
  • Coronar, perifery or cerebral vascular disease last 3 months
  • Familial hypercholesterolemia
  • Change in dose of statins, oestrogen or contraceptives last 3 months
  • Taking drugs which are known to interfere with the plasma level of cholesterol
  • Chronic rheumatoid diseases or other diseases known to affect c-reactive protein
  • Pregnancy
  • Lactation
  • Planning to reduce weight
  • Taking plant sterols

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00485095

Lipidklinikken, Rikshospitalet Radiumhospitalet HF
Oslo, Norway
Rikshospitalet Radiumhospitalet HF, Oslo, Norway
Oslo, Norway
Sponsors and Collaborators
Oslo University Hospital
Mills DA
Principal Investigator: Leiv Ose, MD Lipidklinikken, Rikshospitalet-Radiumhospitalet HF

Publications automatically indexed to this study by Identifier (NCT Number): Identifier: NCT00485095     History of Changes
Other Study ID Numbers: 2.2006.3407
First Posted: June 12, 2007    Key Record Dates
Last Update Posted: July 1, 2011
Last Verified: February 2009

Additional relevant MeSH terms:
Lipid Metabolism Disorders
Metabolic Diseases