Cardiovascular Risk Factors and LCH in Adults
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|ClinicalTrials.gov Identifier: NCT00483925|
Recruitment Status : Unknown
Verified June 2007 by Laikon General District Hospital, Athens.
Recruitment status was: Recruiting
First Posted : June 8, 2007
Last Update Posted : June 8, 2007
Langerhans-cell histiocytosis (LCH) is a rare disease with features of chronic inflammation and hypopituitarism, conditions associated with increased risk of cardiovascular diseases.
Objective: To investigate glucose and lipid metabolism, insulin resistance, structural arterial and functional endothelial properties in patients with multisystem LCH in a prospective, observational study.
Interventions:Cardiovascular risk factors: arterial blood pressure, lipid profile, mathematical indices of insulin resistance (IR), intima media thickness, brachial artery flow mediated dilatation, dynamic indices of IR, pituitary function and C-reactive protein will be estimated in patients with LCH and in a control group matched for gender, age, BMI and smoking habits.
|Condition or disease|
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|Study Type :||Observational|
|Observational Model:||Case Control|
|Official Title:||CARDIOVASCULAR RISK FACTORS IN ADULT PATIENTS WITH MULTISYSTEM LANGERHANS-CELL HISTIOCYTOSIS: EVIDENCE OF GLUCOSE METABOLISM ABNORMALITIES|
|Study Start Date :||September 2005|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00483925
|Contact: Gregory Kaltsas, MD, FRCPfirstname.lastname@example.org|
|Division of Endocrinology, Department of Pathophysiology, Laiko University Hospital,||Recruiting|
|Athens, Greece, 11527|
|Contact: Gregory Kaltsas, MD, FRCP|
|Principal Investigator: Krystallenia I Alexandraki, MD, MSc, PhD|
|Study Director:||Gregory Kaltsas, MD, FRCP||Division of Endocrinology, Department of Pathophysiology, Laiko University Hospital|