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Study of Safety, Tolerability and Efficacy of MK0493 in Obese Patients (0493-008)(COMPLETED)

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ClinicalTrials.gov Identifier: NCT00482638
Recruitment Status : Completed
First Posted : June 5, 2007
Last Update Posted : August 13, 2015
Sponsor:
Information provided by (Responsible Party):
Merck Sharp & Dohme Corp.

Brief Summary:
To assess the effect of MK0493 on body weight, blood pressure, mood, and appetite.

Condition or disease Intervention/treatment Phase
Obesity Drug: MK0493 Phase 2

Study Type : Interventional  (Clinical Trial)
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double
Primary Purpose: Treatment
Study Start Date : May 2004
Actual Primary Completion Date : October 2004
Actual Study Completion Date : October 2004




Information from the National Library of Medicine

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Ages Eligible for Study:   21 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Patient is between 21 and 65 years
  • Patient is able to read and understand and complete study questionnaires
  • Patient is not pregnant or breast-feeding and does not plan to become pregnant for the duration of the study and post-study follow-up period

Exclusion Criteria:

  • Patient has a history of significant psychiatric disorder (such as major depression, bipolar disorder, bulimia, or anorexia nervosa
  • Patient is HIV positive as determined by medical history
  • Patient has undergone surgical treatment for obesity
  • Patient plans to consume more than two 8 ounce glasses of grapefruit juice per day during the study
  • Patient participated in another clinical study involving an investigational drug) within 3 months prior to Visit 1
  • Patient is currently a heavy consumer of alcohol (>2 drinks per day or >14 drinks per week [1 drink is defined as 2 oz hard alcohol, 5 oz wine, 12 oz beer], or uses (including recreational use) any illicit drugs, or has a history of drug or alcohol abuse

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00482638


Sponsors and Collaborators
Merck Sharp & Dohme Corp.
Investigators
Study Director: Medical Monitor Merck Sharp & Dohme Corp.

Responsible Party: Merck Sharp & Dohme Corp.
ClinicalTrials.gov Identifier: NCT00482638     History of Changes
Other Study ID Numbers: 0493-008
2007_571
First Posted: June 5, 2007    Key Record Dates
Last Update Posted: August 13, 2015
Last Verified: August 2015