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Dialectical Cognitive Traumatherapy (DCT) on Patients With Severe PTSD Following Sexual Abuse (PASA)

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified April 2010 by Central Institute of Mental Health, Mannheim.
Recruitment status was:  Active, not recruiting
Information provided by:
Central Institute of Mental Health, Mannheim Identifier:
First received: May 31, 2007
Last updated: April 20, 2010
Last verified: April 2010
The purpose of this study is to determine whether Dialectical Cognitive Traumatherapy is effective in the treatment of severe and chronic Posttraumatic Stress Disorder (PTSD) following childhood sexual abuse.

Condition Intervention Phase
Posttraumatic Stress Disorder
Behavioral: Dialectical Cognitive Therapy
Phase 2

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Dialectical Cognitive Traumatherapy (DCT) on Patients With Severe Posttraumatic Stress Disorder Following Sexual Abuse - A Randomised Controlled Trial

Resource links provided by NLM:

Further study details as provided by Central Institute of Mental Health, Mannheim:

Primary Outcome Measures:
  • PTSD Symptoms (CAPS, SCID, PDS, IESR) [ Time Frame: 1.5 years ]

Secondary Outcome Measures:
  • general psychopathology [ Time Frame: 1.5 years ]
  • change of pain threshold [ Time Frame: 1.5 years ]
  • fMRI: activity of the amygdala [ Time Frame: 6 months ]

Estimated Enrollment: 64
Study Start Date: April 2007
Estimated Study Completion Date: October 2010
Estimated Primary Completion Date: December 2008 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
No Intervention: 1
Waitlist; Treatment as usual
Behavioral: Dialectical Cognitive Therapy
Dialectical Behavior Therapy in Combination with Traumafocused CBT

Detailed Description:
Most studies on psychological treatments for PTSD exclude patients with severe, co-occurring psychopathology. We designed a new treatment (Dialectical Cognitive Trauma Therapy, or DCT) specifically to treat these patients. DCT includes elements of emotion regulation, mindfulness exercises, cognitive and exposure treatment, as well as new elements. This randomized controlled study evaluates the effect of inpatient DCT on these patients.

Ages Eligible for Study:   17 Years and older   (Child, Adult, Senior)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Female
  • Minimum age of 17
  • Childhood sexual abuse
  • Posttraumatic Stress Disorder (criteria of SCID)
  • At least one of the following diagnoses: Anorexia Nervosa, or Bulimia Nervosa, or substance abuse, or substance dependence, or major depression or at least 4 out of 9 criteria for Borderline Personality Disorder

Exclusion Criteria:

  • Diagnosis of schizophrenia
  • Mental retardation
  • Body Mass Index lower than 16.5
  • Acute delirium
  • Perilous selfharming behaviour during the last 4 month
  • Suicide attempt with the distinct intention to die during the last 4 month
  • Unstability (e.g. homelessness, acute victimisation by offender)
  • Pretreatment by DCT
  Contacts and Locations
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Please refer to this study by its identifier: NCT00481000

Central Institute of Mental Health
Mannheim, Germany, 68159
Sponsors and Collaborators
Central Institute of Mental Health, Mannheim
Study Director: Regina Steil, PhD Central Institute of Mental Health
Study Chair: Martin Bohus, PhD Central Institute of Mental Health
Principal Investigator: Anne S Dyer, PhD Central Institute of Mental Health
  More Information

Responsible Party: Prof. Dr. Martin Bohus, Central Institute of Mental Health, Psychosomatic Clinic Identifier: NCT00481000     History of Changes
Other Study ID Numbers: PASA-0230
Study First Received: May 31, 2007
Last Updated: April 20, 2010

Keywords provided by Central Institute of Mental Health, Mannheim:
Dialectical Cognitive Therapy
Clinical Psychology

Additional relevant MeSH terms:
Stress Disorders, Traumatic
Stress Disorders, Post-Traumatic
Trauma and Stressor Related Disorders
Mental Disorders processed this record on April 27, 2017