Opioid Rotation Versus Combination for Chronic Uncontrolled Cancer Pain
For cancer patients with inadequate pain relief, a switch to an alternative opioid is the preferred option for symptomatic improvement. However, multiple opioids are often simultaneously administered for anecdotal reasons.
The present study isdesigned to assess the analgesic profiles of two different strategies in chronic cancer pain: the opioid rotation from oxycodone to transdermal fentanyl and the combination of oral oxycodone and transdermal fentanyl.
|Study Design:||Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Supportive Care
- Change in pain score and treatment success
- Patient satisfaction
|Study Start Date:||February 2006|
|Study Completion Date:||April 2007|
Please refer to this study by its ClinicalTrials.gov identifier: NCT00478101
|Principal Investigator:||Se Hoon Park, MD||Gachon University Gil Medical Center, Incheon, Korea|