Hyperbaric Oxygen Therapy and Angiogenesis in Diabetic Patients With Foot Ulcers
Recruitment status was: Recruiting
Diabetic foot ulcers are a major cause of morbidity and mortality, accounting for approximately two-thirds of all non-traumatic amputations performed in the United States. The cost of foot ulcers in diabetic patients averages almost $28,000 for the two years after diagnosis of the ulcer. Hyperbaric oxygen (HBO) serves as primary or adjunctive therapy for a diverse range of medical conditions. HBO also has been used as an adjunct to antibiotics, debridement, and revascularization in the therapy of chronic, nonhealing wounds associated with diabetes or non-diabetic vascular insufficiency.
The aim of the study is to assess whether hyperoxia induced angiogenesis in diabetic patients with foot ulcers.
Diabetic Foot Ulcers
|Study Design:||Observational Model: Defined Population
Time Perspective: Longitudinal
Time Perspective: Prospective
Please refer to this study by its ClinicalTrials.gov identifier: NCT00475202
|Institute of Hyperbaric Medicine and Wound Care Clinic at Assaf Harofeh Medical Center|
|Zerifin, Israel, 70300|
|Principal Investigator:||Albert Rabinovitz, MD||Assaf-Harofeh Medical Center|
|Study Chair:||Efrati Shai, MD||Assaf-Harofeh Medical Center|