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Intravascular Ultrasound for Hepatocellular Carcinoma Staging

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ClinicalTrials.gov Identifier: NCT00474734
Recruitment Status : Unknown
Verified May 2007 by University Hospital, Geneva.
Recruitment status was:  Recruiting
First Posted : May 17, 2007
Last Update Posted : May 17, 2007
Sponsor:
Information provided by:
University Hospital, Geneva

Study Description
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Brief Summary:

To diagnose hepatocellular carcinoma (HCC) and to determine the extent of the disease, a triphasic CT scan or a magnetic resonance imaging are required. The characterization of hepatic nodules is more difficult when the HCC lesions have a diameter of less than 2 cm.

Since accuracy in the assessment of the number and the size of HCC nodules, as well as of the invasion of blood vessels is crucial to determine outcome after liver transplantation due to tumour recurrence, there is a need for techniques with a higher definition potential.

As a consequence, to improve outcome and to optimize organ allocation, patients on the liver transplantation waiting list might benefit from intravascular ultrasound as an additional examination to complete the pre-transplant tumour staging process.


Condition or disease Intervention/treatment
Hepatocellular Carcinoma Device: Intravascular ultrasound of the liver

Study Design
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Study Type : Observational
Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Longitudinal
Time Perspective: Prospective
Official Title: Intravascular Ultrasound for the Staging of Hepatocellular Carcinoma: a Pilot Study
Study Start Date : May 2007
Estimated Study Completion Date : September 2007

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Ultrasound
U.S. FDA Resources

Groups and Cohorts
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Outcome Measures
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Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

Eligibility Criteria
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Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

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Ages Eligible for Study:   18 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • hepatocellular carcinoma nodules
  • patient on liver transplantation waiting list
  • written informed consent

Exclusion Criteria:

  • thrombosis of hepatic veins or vena cava
Contacts and Locations
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Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00474734


Contacts
Contact: Antoine Hadengue, Prof. +41 22 37 29 340 antoine.hadengue@hcuge.ch

Locations
Switzerland
University Hospital Geneva Recruiting
Geneva, Switzerland
Contact: Andrea De Gottardi, MD PhD    +41 22 37 29 256    andrea.degottardi@hcuge.ch   
Sponsors and Collaborators
University Hospital, Geneva
Investigators
Study Chair: Antoine Hadengue, Prof. University Hospital, Geneva
More Information
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Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

ClinicalTrials.gov Identifier: NCT00474734     History of Changes
Obsolete Identifiers: NCT00472979
Other Study ID Numbers: 07-063
First Posted: May 17, 2007    Key Record Dates
Last Update Posted: May 17, 2007
Last Verified: May 2007

Keywords provided by University Hospital, Geneva:
hepatocellular carcinoma
liver transplantation
staging
intravascular ultrasound

Additional relevant MeSH terms:
Carcinoma
Carcinoma, Hepatocellular
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type
Neoplasms
Adenocarcinoma
 Liver Neoplasms
Digestive System Neoplasms
Neoplasms by Site
Digestive System Diseases
Liver Diseases