Analysis of Human Tear Proteins in Children

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00473278
Recruitment Status : Completed
First Posted : May 15, 2007
Last Update Posted : January 30, 2013
Information provided by (Responsible Party):
University of Colorado, Denver

Brief Summary:
The significance of our study is in the importance of understanding the quality and quantity of proteins in the human tear film, and any unique aspects of tears in children. This pilot study will provide data to plan prospective research to better delineate the utility of tear proteins in diagnosing and following disease status in a non-invasive fashion.

Condition or disease
Eye Disease

Study Type : Observational
Actual Enrollment : 2 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Analysis of Human Tear Proteins in Children: A Pilot Study to Describe the Tear Film Proteome of Pediatric Patients Undergoing Ophthalmic Examination.
Study Start Date : January 2007
Actual Primary Completion Date : June 2009
Actual Study Completion Date : June 2009

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Primary Outcome Measures :
  1. Proteome of Human Tears [ Time Frame: Single Exam ]

Information from the National Library of Medicine

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Ages Eligible for Study:   up to 17 Years   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
children less than 18 years of age

Inclusion Criteria:

  • Less than 18 years of age
  • A parent or legal guardian provide written informed consent to participate
  • Able to cooperate with tear sample collection, or a previously planned sedation for other medical purposes

Exclusion Criteria:

  • Age greater than or equal to 18 years
  • Patients' parents or legal guardians who refuse to sign study consent

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00473278

United States, Colorado
The Childrens Hospital
Denver, Colorado, United States, 80218
Sponsors and Collaborators
University of Colorado, Denver
Principal Investigator: Malik Y. Kahook, MD Rocky Mountain Lions Eye Institute

Responsible Party: University of Colorado, Denver Identifier: NCT00473278     History of Changes
Other Study ID Numbers: 06-1067
First Posted: May 15, 2007    Key Record Dates
Last Update Posted: January 30, 2013
Last Verified: January 2013

Keywords provided by University of Colorado, Denver:
tear protein

Additional relevant MeSH terms:
Eye Diseases