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The Effects of Exercise on Adipokine in Impaired Fasting Glucose or Impaired Glucose Tolerance Patients

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified May 2007 by Yonsei University.
Recruitment status was:  Recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT00472342
First Posted: May 11, 2007
Last Update Posted: May 11, 2007
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Yonsei University
  Purpose

Many adipokines are thought that related with metabolic disturbance such as glucose intolerance, dyslipidemia, and insulin resistance. It is reported that regular physical training could prevent the progression of diabetes from prediabetes and improve the insulin resistance. After physical training, many adipokine levels were changed due to improving insulin resistance.

In this study, we will examine the various adipokine levels such as adiponectin, RBP-4, and adrenomedullin after exercise training through exercise prescription in IFG and IGT patients.


Condition Intervention
Impaired Glucose Tolerance Diabetes Behavioral: exercise prescription

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
Official Title: The Effects of Exercise on Adipokine in Impaired Fasting Glucose or Impaired Glucose Tolerance Patients

Resource links provided by NLM:


Further study details as provided by Yonsei University:

Primary Outcome Measures:
  • Improvements of adipokine levels [ Time Frame: 6 Months ]

Secondary Outcome Measures:
  • Prevention of diabetes [ Time Frame: 1~5 year ]

Estimated Enrollment: 182
Study Start Date: March 2007
Estimated Study Completion Date: December 2007
  Show Detailed Description

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   30 Years to 70 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  1. Age; 30~70
  2. Subjects with IGT and IFG
  3. Subjects with having possibility of exercise stress test
  4. Subjects with having a strong will to this study

Exclusion Criteria:

  1. Age <30 or >70
  2. Cr more than 1.5 mg/dL
  3. AST, ALT levels more than twice as upper normal range
  4. Subjects having past history of coronary artery disease
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00472342


Contacts
Contact: Choon Hee Chung, Prefessor 82-33-741-0506 cchung@yonsei.ac.kr

Locations
Korea, Republic of
Mi Young Lee Recruiting
Wonju, Kangwon-Do, Korea, Republic of, 220-701
Contact: Mi Young Lee, Dr    82-33-741-0681    domoe46@yonsei.ac.kr   
Sponsors and Collaborators
Yonsei University
Investigators
Principal Investigator: Mi Young Lee, Dr Department of Internal Medicine, Yonsei University Wonju College of Medicine
Study Chair: Choon Hee Chung, professor Department of Internal Medicine, Yonsei Univerisity Wonju College of Medicine
  More Information

ClinicalTrials.gov Identifier: NCT00472342     History of Changes
Other Study ID Numbers: kenshin46
First Submitted: May 10, 2007
First Posted: May 11, 2007
Last Update Posted: May 11, 2007
Last Verified: May 2007

Keywords provided by Yonsei University:
impaired glucose tolerance
impaired fasting glucose
diabetes
adipokine
adiponectin
RBP-4
adrenomedullin

Additional relevant MeSH terms:
Glucose Intolerance
Hyperglycemia
Glucose Metabolism Disorders
Metabolic Diseases