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The Effects of Exercise on Adipokine in Impaired Fasting Glucose or Impaired Glucose Tolerance Patients

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified May 2007 by Yonsei University.
Recruitment status was:  Recruiting
Information provided by:
Yonsei University Identifier:
First received: May 10, 2007
Last updated: NA
Last verified: May 2007
History: No changes posted

Many adipokines are thought that related with metabolic disturbance such as glucose intolerance, dyslipidemia, and insulin resistance. It is reported that regular physical training could prevent the progression of diabetes from prediabetes and improve the insulin resistance. After physical training, many adipokine levels were changed due to improving insulin resistance.

In this study, we will examine the various adipokine levels such as adiponectin, RBP-4, and adrenomedullin after exercise training through exercise prescription in IFG and IGT patients.

Condition Intervention
Impaired Glucose Tolerance Diabetes Behavioral: exercise prescription

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
Official Title: The Effects of Exercise on Adipokine in Impaired Fasting Glucose or Impaired Glucose Tolerance Patients

Resource links provided by NLM:

Further study details as provided by Yonsei University:

Primary Outcome Measures:
  • Improvements of adipokine levels [ Time Frame: 6 Months ]

Secondary Outcome Measures:
  • Prevention of diabetes [ Time Frame: 1~5 year ]

Estimated Enrollment: 182
Study Start Date: March 2007
Estimated Study Completion Date: December 2007
  Show Detailed Description


Ages Eligible for Study:   30 Years to 70 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  1. Age; 30~70
  2. Subjects with IGT and IFG
  3. Subjects with having possibility of exercise stress test
  4. Subjects with having a strong will to this study

Exclusion Criteria:

  1. Age <30 or >70
  2. Cr more than 1.5 mg/dL
  3. AST, ALT levels more than twice as upper normal range
  4. Subjects having past history of coronary artery disease
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00472342

Contact: Choon Hee Chung, Prefessor 82-33-741-0506

Korea, Republic of
Mi Young Lee Recruiting
Wonju, Kangwon-Do, Korea, Republic of, 220-701
Contact: Mi Young Lee, Dr    82-33-741-0681   
Sponsors and Collaborators
Yonsei University
Principal Investigator: Mi Young Lee, Dr Department of Internal Medicine, Yonsei University Wonju College of Medicine
Study Chair: Choon Hee Chung, professor Department of Internal Medicine, Yonsei Univerisity Wonju College of Medicine
  More Information Identifier: NCT00472342     History of Changes
Other Study ID Numbers: kenshin46
Study First Received: May 10, 2007
Last Updated: May 10, 2007

Keywords provided by Yonsei University:
impaired glucose tolerance
impaired fasting glucose

Additional relevant MeSH terms:
Glucose Intolerance
Glucose Metabolism Disorders
Metabolic Diseases processed this record on September 19, 2017