Photodynamic Therapy With Verteporfin for Corneal Neovascularization
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|ClinicalTrials.gov Identifier: NCT00471406|
Recruitment Status : Completed
First Posted : May 9, 2007
Last Update Posted : October 17, 2008
Purpose: To investigate the efficacy of photodynamic therapy with verteporfin for the treatment of patients with corneal neovascularization.
Design: Prospective, non-comparative case series. Participants: Eighteen eyes of 18 patients with stable corneal neovascularization who were refractory to conventional treatment.
Methods: The patients were treated with photodynamic therapy with verteporfin (6 mg/m2). Five patients were treated following penetrating keratoplasty, and 2 patients were treated before penetrating keratoplasty. Best corrected visual acuity and anterior segment photography were performed before and after treatment. The length of cumulative blood vessels and area of corneal neovascularization were measured.
Main outcome measures: Vascular occlusion, best corrected visual acuity, cumulative blood vessel length, and corneal neovascularization area.
|Condition or disease||Intervention/treatment||Phase|
|Corneal Neovascularization||Procedure: Photodynamic Therapy with Verteporfin||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00471406
|Study Director:||Kyung chul Yoon, MD||Chonnam natianl university hospital|