Effect of Placental Drainage of Fetal Blood at Cesarean Section on the Incidence of Feto-Maternal Transfusion
Study hypothesis: umbilical cord drainage of fetal blood after delivery of the infant would reduce the incidence of feto-maternal transfusion. Patients were randomized to placental drainage or no drainage at the time of cesarean section. The incidence of fetal to maternal transfusion was noted postoperatively.
Procedure: drainage of placenta of fetal blood
|Study Design:||Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Primary Purpose: Treatment
|Official Title:||Effect of Placental Drainage of Fetal Blood at Cesarean Section on the Incidence of Feto-Maternal Transfusion: A Randomized Controlled Trial|
- Presence/absence of fetal blood in maternal circulation [ Time Frame: within 12 hours postoperatively ]
- no secondary outcome measures [ Time Frame: end of study ]
|Study Start Date:||January 2005|
|Study Completion Date:||January 2006|
86 patients were randomized to placental drainage vs. no drainage of fetal blood at the time of cesarean section. Kleihauer-Betke testing was performed within 12 hours postoperatively to assess the incidence of feto-maternal transfusion. A significant difference was found between the two groups.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00470899
|Study Director:||Laird A Bell, MD, MPH||Lester E. Cox Medical Center|