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Aerobic Capacity and Body Composition in Colon Cancer Patients

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00470782
First Posted: May 8, 2007
Last Update Posted: February 26, 2016
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
AHS Cancer Control Alberta
  Purpose
Recent studies have shown that survival after a colorectal cancer diagnosis may be affected by a person's activity level and body size. This research says that for colorectal cancer patients, the less active and more obese they are, the more likely they are to have a cancer recurrence or die from their cancer. Chemotherapy has been shown to reduce activity levels, fitness, and body size in some cancer patients. However, it is not known how chemotherapy specific for colon cancer patients affects their activity levels, fitness, and body size. The main goal of our study will be to look at how chemotherapy treatments affect the fitness, activity levels, and body size in colon cancer patients. In order to do this, we will measure these variables before chemotherapy treatments, and at 1 and 6 months following the end of treatment. Our results will show how chemotherapy affects fitness, activity levels, and body size in colon cancer patients and provide data to help in designing an exercise intervention specifically for colon cancer survivors.

Condition
Colonic Neoplasms

Study Type: Observational
Study Design: Observational Model: Case-Only
Official Title: Changes in Aerobic Capacity and Body Composition in Colon Cancer Patients Receiving Chemotherapy

Further study details as provided by AHS Cancer Control Alberta:

Enrollment: 40
Study Start Date: October 2007
Study Completion Date: October 2009
Primary Completion Date: October 2009 (Final data collection date for primary outcome measure)
  Show Detailed Description

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
community sample
Criteria

Inclusion Criteria:

  • histologically confirmed colon cancer (Stage III and those Stage II patients deemed high-risk
  • approval of the treating oncologist
  • scheduled to received chemotherapy
  • able to understand and provide written informed consent in English
  • 18+ years of age
  • no uncontrolled co-morbidities (including hypertension, cardiac illness, psychiatric condition, etc.)
  • negative ECG as assessed during maximal graded exercise test

Exclusion Criteria:

  • metastatic or recurrent colon cancer patients
  • pregnancy
  • any uncontrolled medical condition that would be a contraindication to exercise (assessed by treating oncologist)
  • unwilling to attend, travel to or participate in the assessments at all 3 time points

In addition, 10 patients meeting all of the eligibility criteria who are not scheduled to receive chemotherapy will also be recruited to the study to serve as "surgery only" controls.

  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00470782


Locations
Canada, Alberta
Cross Cancer Institute
Edmonton, Alberta, Canada, T6G 1Z2
Sponsors and Collaborators
AHS Cancer Control Alberta
Investigators
Principal Investigator: Kerry Courneya, PhD University of Alberta
  More Information

Responsible Party: AHS Cancer Control Alberta
ClinicalTrials.gov Identifier: NCT00470782     History of Changes
Other Study ID Numbers: GI-5-0064 / ethics 23429
First Submitted: May 7, 2007
First Posted: May 8, 2007
Last Update Posted: February 26, 2016
Last Verified: April 2012

Keywords provided by AHS Cancer Control Alberta:
colonic neoplasms
exercise
body composition
anthropometry

Additional relevant MeSH terms:
Colonic Neoplasms
Colorectal Neoplasms
Intestinal Neoplasms
Gastrointestinal Neoplasms
Digestive System Neoplasms
Neoplasms by Site
Neoplasms
Digestive System Diseases
Gastrointestinal Diseases
Colonic Diseases
Intestinal Diseases