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The Efficacy of Color-Doppler Ultrasonography to Assess the Renal Blood Flow With the Estimation of GFR

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified May 2007 by University of Roma La Sapienza.
Recruitment status was:  Recruiting
Information provided by:
University of Roma La Sapienza Identifier:
First received: May 7, 2007
Last updated: NA
Last verified: May 2007
History: No changes posted
It is generally assumed that renal blood flow is symmetric in the absence of renal artery stenosis. The importance of studying the function of both kidneys separately is because it cannot be assumed that they are functionally equal.The aim of the present study is to evaluate whether this is really in patients with essential hypertension and/or moderate kidneys loss.

Condition Intervention
Hypertension Renal Failure Procedure: Color-Doppler Ultrasound, 99mTc-DTPA scintigraphy

Study Type: Observational
Study Design: Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Cross-Sectional
Time Perspective: Prospective
Official Title: Color-Doppler Ultrasonography vs 99mTc-DTPA Scintigraphy to Assess the Renal Blood Flow

Resource links provided by NLM:

Further study details as provided by University of Roma La Sapienza:

Estimated Enrollment: 2006
Study Start Date: September 2006
Estimated Study Completion Date: May 2007
Detailed Description:
To validate color Doppler ultrasonography of renal arteries for the assessment of renal blood flow (RBF), we comparing left and right RBF estimates and their sum (total RBF) by echo-Doppler with data obtained by 99mTc-DTPA scintigraphy in 50 patients with hypertension and/or moderate renal failure, compared with 30 normal control subjects.

Ages Eligible for Study:   30 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Patients with hypertension
  • Patients with moderate renal insufficiency
  • Normal subjects

Exclusion Criteria:

  • Patients with solitary kidney function
  • Patients with renal artery stenosis
  • Patients underwent renal angioplasty and stenting
  Contacts and Locations
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Please refer to this study by its identifier: NCT00470769

Contact: Rosario Cianci, MD +39335206441

Giorgio Fuiano Recruiting
Catanzaro, Italy, 88020
University of Rome La Sapienza Recruiting
Roma, Italy, 00100
Contact: Rosario Cianci, MD    +39335206441   
Contact: Giorgio Fuiano, MD    +39 0961775360   
Rosario Cianci Recruiting
Rome, Italy, 00100
Sponsors and Collaborators
University of Roma La Sapienza
Principal Investigator: Rosario Cianci, MD Department Of Clinic Medicine, Chair of Nephrology
Study Director: Giorgio Fuiano, MD University of Catanzaro
  More Information Identifier: NCT00470769     History of Changes
Other Study ID Numbers: CR-UR-00001
Study First Received: May 7, 2007
Last Updated: May 7, 2007

Keywords provided by University of Roma La Sapienza:
Color-Doppler Ultrasonography
Renal scintigraphy
Kidney failure

Additional relevant MeSH terms:
Renal Insufficiency
Kidney Diseases
Urologic Diseases processed this record on September 21, 2017