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Ghrelin Levels in Early IVF Pregnancies

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00469807
First Posted: May 7, 2007
Last Update Posted: April 28, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Instituto Valenciano de Infertilidad, IVI VALENCIA
  Purpose
In this study, we have assessed the potential prognostic value for gestational outcome of maternal ghrelin levels at very early stages of IVF pregnancies. In addition, ghrelin responses to meal intake were explored at early gestation.

Condition
Pregnancy

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Maternal Serum Ghrelin Levels in Early IVF Pregnancies: Lack of Prognostic Value for Gestational Outcome and Altered Post-Prandial Responses

Further study details as provided by Instituto Valenciano de Infertilidad, IVI VALENCIA:

Study Start Date: June 2004
Study Completion Date: May 2007
Detailed Description:

Ghrelin is a pleiotropic hormone recently involved in the control of growth and metabolism, whose circulating levels fluctuate in relation to food intake and body mass index. Ghrelin has been detected in the decidualized endometrium, as well as in human and rat placenta, with a distinctive temporal pattern of expression along pregnancy.

Comparison(s): A total of 106 patients undergoing IVF procedures were prospectively recruited. On d-16 and 23 after oocyte retrieval, the patients were subjected to blood sampling after overnight fasting, for determination of serum ghrelin, hCG and progesterone levels. In addition, ghrelin levels were assayed in these groups, 2-h after ingestion of a fixed-calorie meal.

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 50 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Patients undergoing IVF
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00469807


Locations
Spain
Ivi Valencia
Valencia, Spain, 46015
Sponsors and Collaborators
Instituto Valenciano de Infertilidad, IVI VALENCIA
Investigators
Study Chair: Antonio Pellicer, MD Instituto Valenciano de Infertilidad
  More Information

ClinicalTrials.gov Identifier: NCT00469807     History of Changes
Other Study ID Numbers: VLC-CV-0604-507-22
First Submitted: May 3, 2007
First Posted: May 7, 2007
Last Update Posted: April 28, 2017
Last Verified: April 2017

Keywords provided by Instituto Valenciano de Infertilidad, IVI VALENCIA:
Ghrelin
Pregnancy outcome