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Capsaicin-Evoked Pain in Patients With CRPS

This study has been completed.
Information provided by:
Danish Pain Research Center Identifier:
First received: May 1, 2007
Last updated: October 10, 2008
Last verified: October 2008
To evaluate the effect of capsaicin in patients with Complex Regional Pain Syndrome.

CRPS (Complex Regional Pain Syndromes)

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Capsaicin-Evoked Pain in Patients With Complex Regional Pain Syndrome

Resource links provided by NLM:

Further study details as provided by Danish Pain Research Center:

Enrollment: 40
Study Start Date: April 2007
Study Completion Date: January 2008
Detailed Description:

Primary outcome parameters: Capsaicin-induced pain and inflammation.

Secondary outcome parameters: Peripheral sensory and autonomic function.


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Primary care clinic

Inclusion Criteria:

  • Age: 18 or older.
  • Pain in arm or hand > 3 months.
  • Diagnosed with CRPS acc. to diagnostic research criteria (Harder et al., 2005)
  • Inclusion of healthy subjects: age-, gender-, and BMI-matched.

Exclusion Criteria:

  • Other significant disease affecting the parameters measured, including cardiovascular disease.
  • Treatment with anticholinergics, sympathomimetics and parasympathomimetics, and alpha- and beta-adrenergics.
  Contacts and Locations
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Please refer to this study by its identifier: NCT00468390

Danish Pain Research Center, Aarhus University Hospital
Aarhus, Denmark, 8000
Sponsors and Collaborators
Danish Pain Research Center
Study Chair: Troels S Jensen, MD, DMSc Danish Pain Research Center, Aarhus University Hospital
  More Information Identifier: NCT00468390     History of Changes
Other Study ID Numbers: Capsaicin in CRPS
Study First Received: May 1, 2007
Last Updated: October 10, 2008

Additional relevant MeSH terms:
Complex Regional Pain Syndromes
Reflex Sympathetic Dystrophy
Pathologic Processes
Autonomic Nervous System Diseases
Nervous System Diseases
Peripheral Nervous System Diseases
Neuromuscular Diseases
Dermatologic Agents
Sensory System Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs processed this record on September 21, 2017