Comparison of 2 Cefazolin Prophylactic Protocol in Laryngectomy Patients
|Study Design:||Allocation: Randomized
Intervention Model: Parallel Assignment
Primary Purpose: Prevention
|Official Title:||Double Blind Randomised Study of 2 Days and 5 Days Cefazolin Prophylactic Method in Laryngeal Oncologic Surgery|
- wound infection [ Time Frame: prospective ]
- drug complication [ Time Frame: 3 week after surgery ]
|Study Start Date:||June 2004|
|Study Completion Date:||March 2006|
Patients undergoing laryngeal oncologic surgery are at relatively high risk of developing complication.
Efficacy of cefazolin as a prophylactic antibiotic in head and neck surgery was reviewed in many researches  but considering the costs and morbidities of prolonged antibiotic regimen we have presented a prospective and randomized study in 90 patients comparing the efficacy of 2 day over 5 day protocols.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00467948
|Iran, Islamic Republic of|
|Imam khomaini hospital|
|Tehran, Iran, Islamic Republic of, 19799|
|Study Chair:||taghi khorsandi, professor||tehran university of medical science|