Comparison of 2 Cefazolin Prophylactic Protocol in Laryngectomy Patients
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00467948|
Recruitment Status : Completed
First Posted : May 1, 2007
Last Update Posted : May 1, 2007
|Condition or disease||Intervention/treatment||Phase|
|Laryngeal Cancer||Drug: cefazolin||Phase 3|
Patients undergoing laryngeal oncologic surgery are at relatively high risk of developing complication.
Efficacy of cefazolin as a prophylactic antibiotic in head and neck surgery was reviewed in many researches  but considering the costs and morbidities of prolonged antibiotic regimen we have presented a prospective and randomized study in 90 patients comparing the efficacy of 2 day over 5 day protocols.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||90 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||Double Blind Randomised Study of 2 Days and 5 Days Cefazolin Prophylactic Method in Laryngeal Oncologic Surgery|
|Study Start Date :||June 2004|
|Study Completion Date :||March 2006|
- wound infection [ Time Frame: prospective ]
- drug complication [ Time Frame: 3 week after surgery ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00467948
|Iran, Islamic Republic of|
|Imam khomaini hospital|
|Tehran, Iran, Islamic Republic of, 19799|
|Study Chair:||taghi khorsandi, professor||tehran university of medical science|