Genetic Basis of Hemangiomas
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|ClinicalTrials.gov Identifier: NCT00466375|
Recruitment Status : Terminated
First Posted : April 27, 2007
Last Update Posted : August 29, 2017
|Condition or disease||Intervention/treatment|
|Hemangioma, Vascular Anomalies||Genetic: Cheek cell samples or blood sample (4mL) Genetic: Cheek cell sample or blood sample (4mL)|
WHAT IS INVOLVED IN THE RESEARCH STUDY?
- Buccal smear (cheek cells) or small blood sample (4 mL or 1 teaspoon) from child being seen in the Dermatology clinic having infantile hemangioma or vascular anomaly
- Buccal smear (cheek cells) or small blood sample (4 mL or 1 teaspoon) from parents of child
If you and your child agree to be in this study, the following will happen:
- Informed consent and permission to use or disclose your/your child's health information for research purposes will be obtained by Dr. Drolet, the principal investigator, or her research team. You will receive a copy of this consent form.
- A buccal swab or blood sample will be obtained from you and your child; buccal sampling involves rubbing the inside of your cheek and removing cells to perform a genetic test called "Genomewide Association (GWA).
We expect you and your child to be involved in this study until you and your child have the genetic testing performed.
|Study Type :||Observational|
|Actual Enrollment :||300 participants|
|Official Title:||Genetic Basis of Hemangiomas|
|Study Start Date :||April 2007|
|Actual Primary Completion Date :||November 2014|
|Actual Study Completion Date :||May 2016|
Patients with a hemangioma.
Genetic: Cheek cell samples or blood sample (4mL)
DNA will be extracted from cheek cell or blood samples from parents and child having hemangioma.
Patients with a vascular anomaly.
Genetic: Cheek cell sample or blood sample (4mL)
DNA will be extracted from cheek cell or blood samples of parents and child with a vascular anomaly.
- SNP [ Time Frame: 3 years ]
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00466375
|United States, Wisconsin|
|Children's Hospital of Wisconsin|
|Milwaukee, Wisconsin, United States, 53226|
|Principal Investigator:||Beth Drolet, MD||Medical College of Wisconsin|