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Using Community-Based Volunteers to Reach Non-Enrolled School Aged Children Through Community-Directed Treatment of Schistosomiasis in School-Aged Children in Rural Northern Ghana

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ClinicalTrials.gov Identifier: NCT00463931
Recruitment Status : Completed
First Posted : April 20, 2007
Last Update Posted : April 20, 2007
Sponsor:
Information provided by:
DBL -Institute for Health Research and Development

Brief Summary:
Schistosomiasis and soil-transmitted helminhtiasis occur throughout the developing world and are most prevalent in the poorest communitites. These worms have been linked to several nutritional and intellectual deficiencies in many endemic populations worldwide. Helminth control, though crucial has been neglected for varied reasons. Currently, interests towards the control of neglected diseases including schistosomiasis and soil-transmitted helminths has been revived through many interventions including repeated chemotherapy to help improve public health outcomes and prevent long term morbidity. This will contribute to achieving several of the Millennium Development Goals at a favourable cost. A community-directed treatment of human schistosomiasis and STH in school-aged children in rural notrhern Ghana using praziquantel and albendazole is proposed. It is planned to test the hypothesis that community-based volunteers are non-inferior and more cost effective than rural school teachers at reaching school-aged children.

Condition or disease
Schistosomiasis Soil-Transmitted Helminthiasis

Detailed Description:

The primary objectives of the study are:

To compare coverage rate of community based volunteers and rural school teachers in the distribution of praziquantel and albendazole to scholl-aged children To determine the cost effectiveness of using community based volunteers to distribute praziquantel and albendazole to school-aged children in rural Ghana.

Study methods:

A list of all school-aged children (6-15 years) in the study area will be generated from the Navrongo Demographic Surveillance System database and registers produced and given to all school teachers and community based volunteers who will be responsible for the distribution of the antihelminithics. The school teachers and community based volunteers will provide the drugs to both enrolled and non-enrolled school-aged children. Percentage coverage of school-aged children will be the outcome measure and compated between the school teachers and the community based volunteers. Stool and urine samples will be collected from a representative sample (916) of the children for laboratory analysis before the administration of the drugs for baseline data. Sample collection and laboratory analysis will be repeated 6 and 12 months after the first round of chemotherapy.


Study Type : Observational
Enrollment : 916 participants
Observational Model: Case Control
Observational Model: Natural History
Time Perspective: Longitudinal
Time Perspective: Prospective
Official Title: Using Community-Based Volunteers to Reach Non-Enrolled School-Aged Children Through Community-Directed Treatment of Schistosomiasis in School-Aged Children in Rural Northern Ghana
Study Start Date : September 2006
Actual Study Completion Date : January 2007

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Information from the National Library of Medicine

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Ages Eligible for Study:   6 Years to 15 Years   (Child)
Sexes Eligible for Study:   All
Criteria

Inclusion Criteria:

  • Children between 6 and 15 years of age

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00463931


Locations
Ghana
The Navrongo Health Research Centre
Navrongo, Ghana
Sponsors and Collaborators
DBL -Institute for Health Research and Development
Investigators
Principal Investigator: Francis Anto, MD Navrongo Health Research Centre, Ghana

ClinicalTrials.gov Identifier: NCT00463931     History of Changes
Other Study ID Numbers: SRP-GH-FA-06
First Posted: April 20, 2007    Key Record Dates
Last Update Posted: April 20, 2007
Last Verified: April 2007

Keywords provided by DBL -Institute for Health Research and Development:
Schistosomiasis
Soiltransmitted helminthiasis
Community-based volunteer
School based treatment approach

Additional relevant MeSH terms:
Schistosomiasis
Helminthiasis
Trematode Infections
Parasitic Diseases