Prognostic Significance of Fine-Needle Aspiration Cytology Features in Papillary Thyroid Carcinoma

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00459459
Recruitment Status : Completed
First Posted : April 12, 2007
Last Update Posted : April 12, 2007
Information provided by:
National Taiwan University Hospital

Brief Summary:
The purpose of this study is to investigate the relationship between prognosis and fine needle aspiration cytology character of papillary thyroid cancer.

Condition or disease Intervention/treatment
Thyroid Neoplasms Procedure: Fine needle aspiration of the thyroid

Detailed Description:
Papillary thyroid carcinoma is the most common thyroid malignancy worldwide. The influence of clinicopathologic features on prognosis has been examined, but the relationship between cytologic features obtained by fine-needle aspiration (FNA) and prognosis has been minimally studied. We retrospectively studied the cytologic features with computerized morphometry in 83 patients with usual-type papillary thyroid cancer and followed them for more than 10 years except for one with metastasis at diagnosis. The cytologic features of FNA and recurrence of cancer were examined statistically.

Study Type : Observational
Enrollment : 100 participants
Observational Model: Defined Population
Observational Model: Natural History
Time Perspective: Longitudinal
Time Perspective: Retrospective
Study Start Date : January 2006
Actual Study Completion Date : December 2006

Resource links provided by the National Library of Medicine

Drug Information available for: Thyroid
U.S. FDA Resources

Information from the National Library of Medicine

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Ages Eligible for Study:   10 Years to 90 Years   (Child, Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Papillary thyroid cancer diagnosed in NTUH from 1977 to 2000

Exclusion Criteria:

  • Patient without complete medical record

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00459459

Shyang-Rong, Shih
Dou-Liou city, Yun-Lin County, Taiwan
Sponsors and Collaborators
National Taiwan University Hospital
Principal Investigator: Shyang-Rong Shi, MD National Taiwan University Hospital, Yun-Lin Branch Identifier: NCT00459459     History of Changes
Other Study ID Numbers: 200704016R
First Posted: April 12, 2007    Key Record Dates
Last Update Posted: April 12, 2007
Last Verified: April 2007

Additional relevant MeSH terms:
Thyroid Diseases
Thyroid Neoplasms
Endocrine System Diseases
Endocrine Gland Neoplasms
Neoplasms by Site
Head and Neck Neoplasms