Body Plethysmograph Measurements Before and After Methacholine Challenge in Early Childhood
In our previous study of Methacholine Challenge Tests (MCT) in preschool children, we found that wheeze detection was associated with significant reduction in flows and vital capacity values. We hypothesized that this finding is associated with trapped-air rather than the children's loss of cooperation/concentration.
Objectives: To test this hypothesis by attempting plethysmography measurements during MCT.
|Study Design:||Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Cross-Sectional
Time Perspective: Prospective
|Official Title:||Body Plethysmograph Measurements Before and After Methacholine Challenge in Early Childhood|
|Study Start Date:||February 2006|
|Estimated Study Completion Date:||September 2006|
Please refer to this study by its ClinicalTrials.gov identifier: NCT00458627
|Principal Investigator:||Lea Bentur, MD||Rambam medical Center, Haifa, Israel|
|Principal Investigator:||Daphna Vilozni, PhD||Rambam Health Care Campus|