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Invasive Infections in Children With Hemoglobinopathies

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00456443
First Posted: April 5, 2007
Last Update Posted: July 25, 2007
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
HaEmek Medical Center, Israel
  Purpose
Patients diagnosed as having hemoglobinopathies are exposed to serious bacterial infections, principally those patients that underwent splenectomy. Since the introduction of anti pneumococcal vaccine the incidence decreased significantly but other bacteria besides encapsulated bacteria takes place as principal cause of invasive infections. The purpose of this study is to analyse in a retrospective study the incidence of those infections in a group of patients suffering from thalassemia and sickle cell anemia treated in our clinic.

Condition Intervention
Thalassemia Sickle Cell Anemia Procedure: Historical records

Study Type: Observational
Study Design: Observational Model: Defined Population
Observational Model: Natural History
Time Perspective: Cross-Sectional
Time Perspective: Retrospective
Official Title: Invasive Infections in Children With Hemoglobinopathies. A Clinical Descriptive Retrospective Study.

Resource links provided by NLM:


Further study details as provided by HaEmek Medical Center, Israel:

Estimated Enrollment: 200
Study Start Date: January 2006
Study Completion Date: June 2006
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   up to 40 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • All patients treated in the Pediatric Hematology Unit.
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00456443


Locations
Israel
Pediatric Hematology Unit and Pediatric Dpt B - HaEmek Medical Center
Afula, Israel, 18101
Sponsors and Collaborators
HaEmek Medical Center, Israel
Investigators
Study Director: Ariel Koren, MD Pediatric Hematology Unit, Ha'Emek Medical Center
Principal Investigator: Waheeb Sakran, MD Pediatric Dpt B - Ha'Emek Medical Center
  More Information

ClinicalTrials.gov Identifier: NCT00456443     History of Changes
Other Study ID Numbers: 4140905.EMC
First Submitted: April 4, 2007
First Posted: April 5, 2007
Last Update Posted: July 25, 2007
Last Verified: April 2007

Keywords provided by HaEmek Medical Center, Israel:
Thalassemia
Sickle cell anemia
Splenectomy
Infections
Streptococcal Pneumonia

Additional relevant MeSH terms:
Infection
Thalassemia
Anemia, Sickle Cell
Hemoglobinopathies
Anemia, Hemolytic, Congenital
Anemia, Hemolytic
Anemia
Hematologic Diseases
Genetic Diseases, Inborn