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Invasive Infections in Children With Hemoglobinopathies

This study has been completed.
Information provided by:
HaEmek Medical Center, Israel Identifier:
First received: April 4, 2007
Last updated: NA
Last verified: April 2007
History: No changes posted
Patients diagnosed as having hemoglobinopathies are exposed to serious bacterial infections, principally those patients that underwent splenectomy. Since the introduction of anti pneumococcal vaccine the incidence decreased significantly but other bacteria besides encapsulated bacteria takes place as principal cause of invasive infections. The purpose of this study is to analyse in a retrospective study the incidence of those infections in a group of patients suffering from thalassemia and sickle cell anemia treated in our clinic.

Condition Intervention
Thalassemia Sickle Cell Anemia Procedure: Historical records

Study Type: Observational
Study Design: Observational Model: Defined Population
Observational Model: Natural History
Time Perspective: Cross-Sectional
Time Perspective: Retrospective
Official Title: Invasive Infections in Children With Hemoglobinopathies. A Clinical Descriptive Retrospective Study.

Resource links provided by NLM:

Further study details as provided by HaEmek Medical Center, Israel:

Estimated Enrollment: 200
Study Start Date: January 2006
Study Completion Date: June 2006

Ages Eligible for Study:   up to 40 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • All patients treated in the Pediatric Hematology Unit.
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Please refer to this study by its identifier: NCT00456443

Pediatric Hematology Unit and Pediatric Dpt B - HaEmek Medical Center
Afula, Israel, 18101
Sponsors and Collaborators
HaEmek Medical Center, Israel
Study Director: Ariel Koren, MD Pediatric Hematology Unit, Ha'Emek Medical Center
Principal Investigator: Waheeb Sakran, MD Pediatric Dpt B - Ha'Emek Medical Center
  More Information Identifier: NCT00456443     History of Changes
Other Study ID Numbers: 4140905.EMC
Study First Received: April 4, 2007
Last Updated: April 4, 2007

Keywords provided by HaEmek Medical Center, Israel:
Sickle cell anemia
Streptococcal Pneumonia

Additional relevant MeSH terms:
Anemia, Sickle Cell
Anemia, Hemolytic, Congenital
Anemia, Hemolytic
Hematologic Diseases
Genetic Diseases, Inborn processed this record on September 20, 2017