Sequential Laser Iridotomy Using Argon and Q-Switched 532 nm Frequency Doubled Neodymium Yag Laser: A Pilot Study
This study has been completed.
Sponsor:
National University Hospital, Singapore
Information provided by:
National University Hospital, Singapore
ClinicalTrials.gov Identifier:
NCT00452998
First received: March 27, 2007
Last updated: May 12, 2008
Last verified: May 2008
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Purpose
Sequential Laser Iridotomy uses argon and Nd:yag laser in the first and second steps, respectively. Using q-switched 532 nm laser in the second step is hypothesized to be as good and effective as the conventional Nd:yag laser, because it selectively targets pigmented cells and delivers a short pulse duration of 3 nanoseconds, causing less thermal and collateral damage.
| Condition | Intervention |
|---|---|
|
Chronic Angle Closure Glaucoma Primary Angle Closure Primary Angle Closure Suspect Fellow Eyes of Acute Angle Closure Glaucoma |
Procedure: Q-switched fd Nd:yag in Laser Iridotomy |
| Study Type: | Interventional |
| Study Design: | Allocation: Non-Randomized Endpoint Classification: Safety/Efficacy Study Intervention Model: Single Group Assignment Masking: Open Label Primary Purpose: Treatment |
| Official Title: | Sequential Laser Iridotomy Using Argon and Q-Switched 532 nm Frequency Doubled Neodymium Yag Laser: A Pilot Study |
Resource links provided by NLM:
Genetics Home Reference related topics:
early-onset glaucoma
MedlinePlus related topics:
Glaucoma
Drug Information available for:
Neodymium
U.S. FDA Resources
Further study details as provided by National University Hospital, Singapore:
Primary Outcome Measures:
- Visual Acuity
- Intraocular pressure
- Total power delivered by each laser modality
- Iridotomy patency and size
- Pain rating during the procedure
- Anterior segment inflammation
- Endothelial cell count
- Cataract progression
- Rate of complications
| Estimated Enrollment: | 10 |
| Study Start Date: | November 2006 |
| Study Completion Date: | December 2007 |
| Primary Completion Date: | December 2007 (Final data collection date for primary outcome measure) |
Show Detailed Description
Eligibility| Ages Eligible for Study: | 22 Years and older (Adult, Senior) |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
Criteria
Inclusion Criteria:
- More than 21 years old
- Able to give informed consent
- Diagnosis of either: chronic angle closure glaucoma (CACG), primary angle closure (PAC), primary angle closure suspect (PACS) or fellow eyes of acute angle closure glaucoma (AACG), and in need of a laser iridotomy
Exclusion Criteria:
- History of any prior laser treatment or intraocular surgery to the eye
- History of any corneal disease
- Any ocular infection/ inflammation within the last two months
- Inability to give informed consent
Contacts and Locations
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To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00452998
Please refer to this study by its ClinicalTrials.gov identifier: NCT00452998
Locations
| Singapore | |
| National University Hospital | |
| Singapore, Singapore, 119074 | |
Sponsors and Collaborators
National University Hospital, Singapore
Investigators
| Principal Investigator: | Paul Chew, FRCSEd,MMed | National University Hospital, Singapore |
More Information
Publications:
| Responsible Party: | Cecilia Aquino, MD, National University Hospital, Singapore |
| ClinicalTrials.gov Identifier: | NCT00452998 History of Changes |
| Other Study ID Numbers: | DSRB A/06/293 |
| Study First Received: | March 27, 2007 |
| Last Updated: | May 12, 2008 |
| Health Authority: | Singapore: Health Sciences Authority |
Keywords provided by National University Hospital, Singapore:
|
Sequential Laser Iridotomy Q-Switched 532 nm Laser Frequency Doubled Neodymium Yag Laser |
Additional relevant MeSH terms:
|
Glaucoma Glaucoma, Angle-Closure Acute Disease Ocular Hypertension |
Eye Diseases Disease Attributes Pathologic Processes |
ClinicalTrials.gov processed this record on September 26, 2016