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Correlation of 6-Minute Walk Test and Neuromuscular Parameters in the Elderly

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified January 2006 by National Taiwan University Hospital.
Recruitment status was:  Recruiting
Information provided by:
National Taiwan University Hospital Identifier:
First received: March 22, 2007
Last updated: NA
Last verified: January 2006
History: No changes posted

The six-minute walk test had been used to assessment the cardiopulmonary parameter in patients with lung and heart disease. And it has good reliability and validity. It has been used extensively in research into the aerobic capacity in patients of peripheral vascular disease, neural system disease, and even the muscular-skeletal system disease, such as osteoarthritis, total hip or knee arthroplasty. There were studies investigate the predictors based on cardiopulmonary factors, neuromuscular and skeletal factors of the six-minute walk distance. But the last is the neuromuscular and skeletal factors.

The purpose of this study is to investigate the correlations between the six-minute walk distance and neuromuscular parameters: muscle function (including muscle endurance, muscle strength and muscle power), knee proprioception, and standing balance. For that it could be more useful for evaluation and treatment patients in clinic.

The study was planed to select 100 subjects, they are older than 65 years old with independent walking and without any diagnosis or symptoms about cardiopulmonary or neural disease. The evaluation are including knee proprioception (closed chain, active-active test), six-minute walk test, one leg standing balance test (open and close eyes for 30 seconds), quadriceps muscle strength at velocities of 600/s,1200/s and 1800/s, quadriceps muscle power at 1800/s, and quadriceps muscle endurance.

To investigate the correlations between the six-minute walk distance and characteristics of subjects, the correlations between six-minute walk distance and neuromuscular parameters, including quadriceps muscle function (strength, endurance and power), knee proprioception, and one leg standing balance. And to analyze what’s the most contribution to the six-minute walk distance.

Condition Intervention Phase
Device: Isokinetic test
Phase 1

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Diagnostic
Official Title: Correlation of 6-Minute Walk Test and Neuromuscular Parameters in the Elderly: Knee Proprioception, Standing Balance, Quadriceps Muscle Strength, Endurance, and Torque Acceleration Energy

Resource links provided by NLM:

Further study details as provided by National Taiwan University Hospital:

Primary Outcome Measures:
  • six-minute walking test
  • knee joint reposition test
  • knee joint muscle strength
  • ankle joint muscle strength
  • knee joint muscle endurance
  • one leg standing balance

Estimated Enrollment: 100
Study Start Date: November 2006
Estimated Study Completion Date: March 2007

Ages Eligible for Study:   65 Years to 85 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • older than 65 years old
  • independent walking

Exclusion Criteria:

  • diagnosis or symptoms about cardiopulmonary or neural disease
  • depression
  Contacts and Locations
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Please refer to this study by its identifier: NCT00451737

Jan Mei Hwa Recruiting
Taipei, Taiwan
Contact: Jan Mei Hwa, Mater    886-2-3322-8138   
Contact: Han Yueh Chin    886-2-3322-8138   
Sponsors and Collaborators
National Taiwan University Hospital
Study Director: Jan Mei Hwa, MS kinesiology laborary of physical therapy in NTU
  More Information Identifier: NCT00451737     History of Changes
Other Study ID Numbers: 9461712111
Study First Received: March 22, 2007
Last Updated: March 22, 2007

Keywords provided by National Taiwan University Hospital:
Six-minute walk test
Neuromuscular system
Influence factors processed this record on April 25, 2017