Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials

Metabolic Effects of Cocaine

This study has been completed.
National Alliance for Research on Schizophrenia and Depression
Information provided by:
National Institute on Drug Abuse (NIDA) Identifier:
First received: March 22, 2007
Last updated: April 30, 2013
Last verified: October 2002

The goal of this this study is to elucidate the role of the HPA axis in the pathophysiology of cocaine dependence

Condition Intervention
Cocaine Dependence
Drug: cocaine
Drug: hydrocortisone

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Double-Blind
Official Title: Elucidating the Role of the Hypothalamic-Pituitary-Adrenal (HPA) Axis in the Mechanisms Underlying Cocaine Dependence

Resource links provided by NLM:

Further study details as provided by National Institute on Drug Abuse (NIDA):

Estimated Enrollment: 15

Ages Eligible for Study:   21 Years to 49 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Individuals with DSM IV diagnosis of cocaine dependence, medically healthy

Exclusion Criteria:

  • Other than cocaine dependence DSM-IV axis I diagnosis
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00451230

United States, Massachusetts
Massachusetts General Hospital
Boston, Massachusetts, United States, 02116
Sponsors and Collaborators
National Alliance for Research on Schizophrenia and Depression
Principal Investigator: Igor Elman MGH
  More Information

No publications provided by National Institute on Drug Abuse (NIDA)

Additional publications automatically indexed to this study by Identifier (NCT Number): Identifier: NCT00451230     History of Changes
Other Study ID Numbers: 2000p 000323, DA#14410
Study First Received: March 22, 2007
Last Updated: April 30, 2013
Health Authority: United States: Federal Government

Keywords provided by National Institute on Drug Abuse (NIDA):
craving, insulin, leptin processed this record on March 01, 2015