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Procedural Learning in Participants With ADHD

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified January 2007 by Shaare Zedek Medical Center.
Recruitment status was:  Not yet recruiting
Information provided by:
Shaare Zedek Medical Center Identifier:
First received: March 11, 2007
Last updated: March 12, 2007
Last verified: January 2007
Skill acquisition refers to the process of improvement of performance following practice experience. This process is the basis for generation of a long-lasting memory. Individuals with Attention Deficit Hyperactivity Disorder (ADHD) have been shown to be impaired on some performance aspects of previously learned skills, an impairment that is often ameliorated, at least temporarily, by psychostimulant medication (the standard therapy in ADHD). The proposed study aims to define the course of learning and of generation of long-term memory consolidation in individuals with ADHD, and to essay the effectiveness of psychostimulant medication on both the learning and retention of the skills.

Condition Intervention Phase
Attention Deficit Hyperactivity Disorder
Procedure: Methylphenidate
Early Phase 1

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Double-Blind

Resource links provided by NLM:

Further study details as provided by Shaare Zedek Medical Center:

Detailed Description:
Skill Acquisition and the Evolution of Long Term Procedural Memory in participants with ADHD: The Effect of Methylphenidate

Ages Eligible for Study:   12 Years to 50 Years   (Child, Adult)
Sexes Eligible for Study:   All

Inclusion Criteria:

  • Full scale IQ score of 85 or above
  Contacts and Locations
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Please refer to this study by its identifier: NCT00446537

Contact: Esther Adi-Japha, PhD 972-3-5318704

Neuropediatric Unit Not yet recruiting
Jerusalem, Israel, 91031
Contact: Esther Adi-Japha, PhD    +972-3-5318704   
Principal Investigator: Ruth Shalev, MD         
Sponsors and Collaborators
Shaare Zedek Medical Center
Principal Investigator: Esther Adi-Japha, PhD Bar-Ilan University, Israel
Study Chair: Ruth Shalev, MD Shaare Zedek Medial Center
  More Information Identifier: NCT00446537     History of Changes
Other Study ID Numbers: 240446
Study First Received: March 11, 2007
Last Updated: March 12, 2007

Keywords provided by Shaare Zedek Medical Center:
Skill Acquisition and the Evolution of Long Term Procedural Memory in participants with ADHD: The Effect of Methylphenidate

Additional relevant MeSH terms:
Attention Deficit Disorder with Hyperactivity
Attention Deficit and Disruptive Behavior Disorders
Neurodevelopmental Disorders
Mental Disorders
Central Nervous System Stimulants
Physiological Effects of Drugs
Dopamine Uptake Inhibitors
Neurotransmitter Uptake Inhibitors
Membrane Transport Modulators
Molecular Mechanisms of Pharmacological Action
Dopamine Agents
Neurotransmitter Agents processed this record on May 25, 2017