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Procedural Learning in Participants With ADHD

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ClinicalTrials.gov Identifier: NCT00446537
Recruitment Status : Unknown
Verified January 2007 by Shaare Zedek Medical Center.
Recruitment status was:  Not yet recruiting
First Posted : March 13, 2007
Last Update Posted : March 13, 2007
Sponsor:
Information provided by:
Shaare Zedek Medical Center

Brief Summary:
Skill acquisition refers to the process of improvement of performance following practice experience. This process is the basis for generation of a long-lasting memory. Individuals with Attention Deficit Hyperactivity Disorder (ADHD) have been shown to be impaired on some performance aspects of previously learned skills, an impairment that is often ameliorated, at least temporarily, by psychostimulant medication (the standard therapy in ADHD). The proposed study aims to define the course of learning and of generation of long-term memory consolidation in individuals with ADHD, and to essay the effectiveness of psychostimulant medication on both the learning and retention of the skills.

Condition or disease Intervention/treatment Phase
Attention Deficit Hyperactivity Disorder Procedure: Methylphenidate Early Phase 1

Detailed Description:
Skill Acquisition and the Evolution of Long Term Procedural Memory in participants with ADHD: The Effect of Methylphenidate

Study Type : Interventional  (Clinical Trial)
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Double

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Ages Eligible for Study:   12 Years to 50 Years   (Child, Adult)
Sexes Eligible for Study:   All
Criteria

Inclusion Criteria:

  • Full scale IQ score of 85 or above

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To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00446537


Contacts
Contact: Esther Adi-Japha, PhD 972-3-5318704 japhae@mail.biu.ac.il

Locations
Israel
Neuropediatric Unit Not yet recruiting
Jerusalem, Israel, 91031
Contact: Esther Adi-Japha, PhD    +972-3-5318704    japhae@mail.biu.ac.il   
Principal Investigator: Ruth Shalev, MD         
Sponsors and Collaborators
Shaare Zedek Medical Center
Investigators
Principal Investigator: Esther Adi-Japha, PhD Bar-Ilan University, Israel
Study Chair: Ruth Shalev, MD Shaare Zedek Medial Center

ClinicalTrials.gov Identifier: NCT00446537     History of Changes
Other Study ID Numbers: 240446
First Posted: March 13, 2007    Key Record Dates
Last Update Posted: March 13, 2007
Last Verified: January 2007

Keywords provided by Shaare Zedek Medical Center:
Skill Acquisition and the Evolution of Long Term Procedural Memory in participants with ADHD: The Effect of Methylphenidate

Additional relevant MeSH terms:
Attention Deficit Disorder with Hyperactivity
Attention Deficit and Disruptive Behavior Disorders
Neurodevelopmental Disorders
Mental Disorders
Methylphenidate
Central Nervous System Stimulants
Physiological Effects of Drugs
Dopamine Uptake Inhibitors
Neurotransmitter Uptake Inhibitors
Membrane Transport Modulators
Molecular Mechanisms of Pharmacological Action
Dopamine Agents
Neurotransmitter Agents