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Blood Sample Collection and Health Information Collection From Patients With Invasive Breast Cancer and Their Brothers and Sisters

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified July 2009 by National Cancer Institute (NCI).
Recruitment status was:  Recruiting
Information provided by:
National Cancer Institute (NCI) Identifier:
First received: March 7, 2007
Last updated: July 9, 2013
Last verified: July 2009

RATIONALE: Collecting blood samples and health information from patients with invasive breast cancer and from their brothers and sisters over time may help the study of cancer in the future.

PURPOSE: This study is collecting blood samples and health information over time from patients with invasive breast cancer and from their brothers and sisters.

Condition Intervention
Breast Cancer Other: biologic sample preservation procedure Other: informational intervention

Study Type: Observational
Official Title: Breast Cancer Siblings Database

Resource links provided by NLM:

Further study details as provided by National Cancer Institute (NCI):

Primary Outcome Measures:
  • Collection of blood samples and medical and background information

Estimated Enrollment: 1000
Study Start Date: January 2001
Primary Completion Date: December 2004 (Final data collection date for primary outcome measure)
Detailed Description:


  • Collect blood samples and medical and background information from patients with invasive breast cancer and their affected or unaffected siblings.

OUTLINE: Patients and their siblings undergo blood collection. They also complete medical and background questionnaires.

Patients and their siblings are followed annually for 5 years.

PROJECTED ACCRUAL: A total of 1,000 patients and siblings will be accrued for this study.


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes


  • Meets 1 of the following criteria:

    • Pathologically confirmed invasive breast cancer (patient)

      • No ductal carcinoma in situ
    • Affected OR unaffected sibling

      • Affected sibling must have had (or currently has) breast cancer only
      • Unaffected sibling must be female
      • No deceased siblings
      • Must be a full-blood related sibling
  • Patients receiving treatment on clinical trial ECOG-E1Y97 or ECOG-E3Y92 are not eligible


  • Not specified


  • Not specified
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00445562

United States, California
GenBasix Incorporated Recruiting
Duarte, California, United States, 91010
Contact: Richard A. Shapiro, MD    800-248-4908      
Sponsors and Collaborators
GenBasix Incorporated
Study Chair: Richard A. Shapiro, MD GenBasix Incorporated
  More Information Identifier: NCT00445562     History of Changes
Other Study ID Numbers: GENBASIX-00127
CDR0000529353 ( Registry Identifier: PDQ (Physician Data Query) )
Study First Received: March 7, 2007
Last Updated: July 9, 2013

Keywords provided by National Cancer Institute (NCI):
male breast cancer
recurrent breast cancer
stage IA breast cancer
stage IB breast cancer
stage II breast cancer
stage IIIA breast cancer
stage IIIB breast cancer
stage IIIC breast cancer
stage IV breast cancer

Additional relevant MeSH terms:
Breast Neoplasms
Neoplasms by Site
Breast Diseases
Skin Diseases processed this record on September 21, 2017