D3-GHR Polymorphism and Turner Syndrome
The protein polymorphism of the growth hormone receptor characterized by the genomic deletion of exon 3 has been linked to the magnitude of the first-year-growth response to growth hormone (GH) in girls with Turner syndrome.
Objective: to study the long-term effect of GH therapy in Turner syndrome in correlation to this GHR polymorphism in a mainly retrospective design (chart-review).
|Official Title:||D3-Growth Hormone Receptor Polymorphism and Total Effect of Recombinant Human Growth Hormone on Growth in Girls With Turner Syndrome|
Please refer to this study by its ClinicalTrials.gov identifier: NCT00443144
|Tübingen, Germany, 72076|
|Principal Investigator:||Gerhard Binder, M.D. PhD||University-Children's Hospital Tübingen|