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Comparison of Ultrasonic Pachymetry With Orbscan in Corneal Haze

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00439114
First Posted: February 23, 2007
Last Update Posted: February 23, 2007
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Baskent University
  Purpose
This study is planned to compare the results of ultrasonic and Orbscan pachymetry in corneal haze not related to surgery. Corneal haze is graded with slit-lamp by a single examiner. Ultrasonic and Orbscan II pachymetry measurements are obtained. Paired t and Kruskal-Wallis tests are used to evaluate the difference between ultrasonic and Orbscan pachymetry measurements. Correlation of the two methods and haze grade is determined with Kendall’s tau-b correlation analysis.

Condition
Corneal Opacity

Study Type: Observational
Study Design: Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Cross-Sectional
Time Perspective: Prospective
Official Title: Comparison of Ultrasonic Pachymetry With Orbscan in Corneal Haze

Resource links provided by NLM:


Further study details as provided by Baskent University:

Estimated Enrollment: 40
Study Start Date: July 2005
Estimated Study Completion Date: June 2006
Detailed Description:
We planned this study to compare the results of ultrasonic and Orbscan pachymetry in corneal haze not related to surgery. In this institutional based, prospective, controlled clinical trial subjects with corneal haze not related to surgery are included. Normal eyes are used as control group to calculate the customized acoustic factor. Corneal haze is graded with slit-lamp by a single examiner. Ultrasonic and Orbscan II pachymetry measurements are obtained by one technician each masked to the other measurement. Paired t and Kruskal-Wallis tests are used to evaluate the difference between ultrasonic and Orbscan pachymetry measurements. Correlation of the two methods and haze grade is determined with Kendall’s tau-b correlation analysis. According to the results of the study, we will determine which method is accurate in subjects with corneal haze.
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 71 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Patients with significant corneal haze on slit-lamp are included in the study group. 50 eyes of 50 age-matched patients with normal eye and clear cornea are included in the control group. Only one eye of each subject is included.

Exclusion Criteria:

  • Exclusion criteria to participate in the study are previous ocular surgery, history of contact lens use, glaucoma, and topical ocular medication use, excluding artificial tears.
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00439114


Locations
Turkey
Baskent University, Faculty of Medicine, Adana Hospital
Adana, N.a., Turkey, 01250
Sponsors and Collaborators
Baskent University
Investigators
Principal Investigator: Rana Altan-Yaycioglu, M.D. Baskent University, Faculty of Medicine, Department of Ophthalmology
  More Information

Publications:
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
ClinicalTrials.gov Identifier: NCT00439114     History of Changes
Other Study ID Numbers: KA05/207
First Submitted: February 21, 2007
First Posted: February 23, 2007
Last Update Posted: February 23, 2007
Last Verified: February 2007

Keywords provided by Baskent University:
Corneal topography, corneal opacity, keratitis, trachoma

Additional relevant MeSH terms:
Corneal Opacity
Corneal Diseases
Eye Diseases