Glucose in Dialysis Water in Non-diabetics

This study has been completed.
Information provided by:
Regional Hospital Holstebro Identifier:
First received: February 20, 2007
Last updated: September 14, 2015
Last verified: September 2007

The purposes are

  1. to measure the effect of dialysis with glucose on blood pressure, pulse rate, plasma concentration of glucose, plasma concentrations of glucagon, growth hormone, renin, angiotensin II, endothelin and body temperature, and
  2. to analysis the relationship between changes in blood pressure on the one hand and changes in vasoactive hormones on the other

Condition Intervention Phase
Renal Failure, Chronic
Procedure: dialysis with glucose in dialysis water
Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Pharmacodynamics Study
Intervention Model: Crossover Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Effect of Glucose in Dialysis Water on Blood Pressure and Vasoactive Hormones in Dialysis Patients

Resource links provided by NLM:

Further study details as provided by Regional Hospital Holstebro:

Primary Outcome Measures:
  • Effect of glucose in dialysis water on blood pressure, insulin and vasoactive hormones [ Time Frame: one week ]

Secondary Outcome Measures:
  • Relationship between changes in blood pressure and changes in hormones during treatment [ Time Frame: one week ]

Enrollment: 18
Study Start Date: May 2006
Study Completion Date: May 2007
Detailed Description:
Measurement of hormones and blood pressure during dialysis treatment.

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  1. Age > 18 years,
  2. Both men and women,
  3. Dialysis treatment for at least three months

Exclusion Criteria:

  1. Heart failure,
  2. Chronic liver disease,
  3. Diabetes mellitus,
  4. Malignant disease,
  5. Nephrotic syndrome,
  6. Lack of compliance, 7 Unwillingness to participate
  Contacts and Locations
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Please refer to this study by its identifier: NCT00439023

Holstebro Hospital
Holstebro, Denmark, 7500
Sponsors and Collaborators
Regional Hospital Holstebro
Study Chair: Erling B Pedersen, Professor Regional Hospital Holstebro
  More Information Identifier: NCT00439023     History of Changes
Other Study ID Numbers: MED.RES.2007.01.EBP 
Study First Received: February 20, 2007
Last Updated: September 14, 2015
Health Authority: Denmark: The Regional Committee on Biomedical Research Ethics

Keywords provided by Regional Hospital Holstebro:
Chronic renal failure, dialysis, hemodialysis,

Additional relevant MeSH terms:
Kidney Failure, Chronic
Renal Insufficiency
Kidney Diseases
Renal Insufficiency, Chronic
Urologic Diseases processed this record on May 26, 2016