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Glucose in Dialysis Water in Diabetics With Chronic Renal Failure

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ClinicalTrials.gov Identifier: NCT00438503
Recruitment Status : Completed
First Posted : February 22, 2007
Last Update Posted : September 15, 2015
Sponsor:
Information provided by:
Regional Hospital Holstebro

Brief Summary:
The purposes are 1. to measure the effect of dialysis with glucose in dialysis water on blood pressure, pulse rate, plasma concentration of glucose, plasma concentrations og insulin, glucagon, growth hormone, renin, angiotensin II, endothelin and body temperature, and 2. to analyse the relationship between the changes in blood pressure and changes in vasoactive hormones

Condition or disease Intervention/treatment Phase
Renal Failure, Chronic Diabetic Nephropathies Procedure: Procedure Phase 4

Detailed Description:
The relationship between blood pressure during dialysis treatment and vasoactive hormones are studied. This includes measurements of plasma concentration of glucose, plasma concentrations og insulin, glucagon, growth hormone, renin, angiotensin II, endothelin

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 18 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Effect of Glucose in Dialysis Water in Diabetics With Chronic Renal Failure on Blood Pressure, Pulse Rate, Plasma Glucose, Plasma Concentrations of Insulin, Growth Hormone, Renin, Angiotensin II, Endothelin and Body Temperature
Study Start Date : May 2006
Study Completion Date : May 2007

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U.S. FDA Resources




Primary Outcome Measures :
  1. Effect og glucose in dialysis water on blood pressure, plasma glucose and hormones in plasma

Secondary Outcome Measures :
  1. Relationship between changes in blood pressure and and changes in hormones


Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  1. Age > 18 years,
  2. Both men and women,
  3. Dialysis treatment for at least three month due to diabetic nephropathy

Exclusion Criteria:

  1. Heart failure,
  2. Lung insufficiency,
  3. Chronic liver disease,
  4. Malignant disease,
  5. Nephrotic syndrome,
  6. Lack of compliance,
  7. Unwillingness to participate

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00438503


Locations
Denmark
Holstebro Hospital
Holstebro, Denmark, 7500
Sponsors and Collaborators
Regional Hospital Holstebro
Investigators
Study Chair: Erling B Pedersen, Professor Regional Hospital Holstebro

ClinicalTrials.gov Identifier: NCT00438503     History of Changes
Other Study ID Numbers: MED.RES.2007.02.EBP
First Posted: February 22, 2007    Key Record Dates
Last Update Posted: September 15, 2015
Last Verified: September 2007

Keywords provided by Regional Hospital Holstebro:
Hemodialysis, diabetes mellitus,
Chronic renal failure, dialysis ,

Additional relevant MeSH terms:
Renal Insufficiency
Diabetic Nephropathies
Kidney Failure, Chronic
Renal Insufficiency, Chronic
Kidney Diseases
Urologic Diseases
Diabetes Complications
Diabetes Mellitus
Endocrine System Diseases