Color Flow Doppler Ultrasound in Subclinical Thyroid Dysfunction

The recruitment status of this study is unknown because the information has not been verified recently.
Verified February 2007 by HaEmek Medical Center, Israel.
Recruitment status was  Not yet recruiting
Information provided by:
HaEmek Medical Center, Israel Identifier:
First received: February 19, 2007
Last updated: NA
Last verified: February 2007
History: No changes posted
Overt hyperthyroidism and hypothyroidism are associated with inverted hemodynamic changes.Regional blood flow disturbances (including intrathyroidal) were also reported in these thyroid disorders. The purpose of this study is to investigate the thyroid vascularity and blood flow by Color Flow Doppler Sonography in patients with subclinical thyroid dysfunction

Subclinical Hypothyroidism
Thyroid Dysfunction

Study Type: Observational
Study Design: Observational Model: Case Control
Primary Purpose: Screening
Time Perspective: Cross-Sectional
Time Perspective: Prospective

Resource links provided by NLM:

Further study details as provided by HaEmek Medical Center, Israel:

Estimated Enrollment: 60
Study Start Date: February 2007
Estimated Study Completion Date: February 2008
Detailed Description:
Color Flow Doppler Sonography (CFDS) has become in the last years an increasing procedure to assess the thyroid blood flow. Previous studies showed specific changes of thyroid blood flow in hyperthyroidism, Hashimoto's thyroiditis and thyroid nodules when investigated by CFDS. Subclinical hyperthyroidism and hypothyroidism are common laboratory findings, defined by normal thyroid hormones concentrations along with ,respectively,decreased or increase Thyroid stimulating hormone (TSH) level. We purpose to investigate thyroid vascularity by CFDS in patients with subclinical hyperthyroidism or hypothyroidism and compared them with euthyroid patients.

Ages Eligible for Study:   18 Years to 75 Years   (Adult, Senior)
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • patients with subclinical hypothyroidism or hyperthyroidism
  • patients with thyroid nodules and normal thyroid function

Exclusion Criteria:

  • patients who are taking thyroxine, antithyroid drugs, lithium or amiodarone
  • patients who had thyroid surgery or radioiodine therapy
  • patients with NYHA class 3 or 4 heart failure
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Please refer to this study by its identifier: NCT00437931

Contact: Avraham Ishay, MD 972-4-6495556
Contact: Rafael Luboshitzky, MD 972-4-5495553

Haemek Medical Center, Department of Radiology Not yet recruiting
Afula, Israel, 18101
Sub-Investigator: Leonid Chervinsky, MD         
Sponsors and Collaborators
HaEmek Medical Center, Israel
Principal Investigator: Avraham Ishay, MD Haemek Medical Center, Endocrine Institute, Afula, Israel
Study Chair: Leonid Chervinsky Haemek Medical Center, Department of Radiology, Afula , Israel
Study Chair: Rafael Luboshitzky, MD Haemek Medical Center, Endocrine Institute, Afula, Israel
  More Information Identifier: NCT00437931     History of Changes
Other Study ID Numbers: 006-07-EMC 
Study First Received: February 19, 2007
Last Updated: February 19, 2007
Health Authority: Israel: Ethics Commission

Keywords provided by HaEmek Medical Center, Israel:
thyroid dysfunction

Additional relevant MeSH terms:
Thyroid Diseases
Endocrine System Diseases processed this record on August 23, 2016