A New Radiation Therapy Planning System in Patients Undergoing Radiation Therapy for Cancer
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ClinicalTrials.gov Identifier: NCT00436397 |
Recruitment Status
:
Completed
First Posted
: February 19, 2007
Last Update Posted
: February 12, 2010
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RATIONALE: A new radiation therapy planning system may help doctors plan better treatment for patients with cancer.
PURPOSE: This clinical trial is studying a new radiation therapy planning system in patients undergoing radiation therapy for extracranial cancer.
Condition or disease | Intervention/treatment | Phase |
---|---|---|
Unspecified Adult Solid Tumor, Protocol Specific | Radiation: radiation therapy | Not Applicable |
OBJECTIVES:
- Determine the ability of the Radionics Body System™ to immobilize and re-localize patients receiving radiotherapy to extra-cranial sites of cancer.
- Determine the accuracy of radiation dose calculations for extra-cranial sites of cancer when using the XPLAN™-intensity modulated radiation therapy (XPLAN™/IMRT) integrated software in this system.
OUTLINE: Patients receiving radiotherapy have a Body Localizer cast constructed and undergo a CT scan while immobilized in the Body Localizer. Patients undergo another CT scan in the treatment position using the standard alpha cradle. The XPLAN™-intensity modulated radiation therapy (XPLAN™/IMRT)-generated treatment plan is compared to the standard treatment plan to verify that the calculated dose is within 2-3 percent of the planned dose using standard technique. Patients undergo sets of CT scans 3 additional times over the next few weeks for a total of 8 CT scans Patients may undergo additional CT scans before and after radiotherapy treatments for a maximum of 5 CT scans per week performed over the course of radiotherapy.
PROJECTED ACCRUAL: Approximately 60 patients will be accrued for this study.
Study Type : | Interventional (Clinical Trial) |
Estimated Enrollment : | 60 participants |
Primary Purpose: | Treatment |
Official Title: | Evaluation of the Radionics Body Localizer System and XPLAN/IMRT for Extra-Cranial Sites: A Pilot Study |
Study Start Date : | June 2002 |
Actual Study Completion Date : | August 2005 |

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Ages Eligible for Study: | Child, Adult, Senior |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
DISEASE CHARACTERISTICS:
-
Cancer for which a course of radiotherapy to an extra-cranial site is required
- Head and neck sites excluded
- Initial treatment field (or cone down field) must be no greater than 12 X 10 cm
PATIENT CHARACTERISTICS:
Age
- Not specified
Performance status
- Not specified
Life expectancy
- Not specified
Hematopoietic
- Not specified
Hepatic
- Not specified
Renal
- Not specified
Cardiovascular
- No right heart insufficiency
Other
- Not pregnant or nursing
- Fertile patients must use effective contraception
- Weight must not exceed 150 kilograms (330 pounds)
PRIOR CONCURRENT THERAPY:
Biologic therapy
- Not specified
Chemotherapy
- Not specified
Endocrine therapy
- Not specified
Radiotherapy
- See Disease Characteristics
Surgery
- Not specified

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00436397
United States, Pennsylvania | |
Fox Chase Cancer Center - Philadelphia | |
Philadelphia, Pennsylvania, United States, 19111-2497 |
Study Chair: | Steven Seigenberg, MD | Fox Chase Cancer Center |
ClinicalTrials.gov Identifier: | NCT00436397 History of Changes |
Other Study ID Numbers: |
CDR0000304713 P30CA006927 ( U.S. NIH Grant/Contract ) FCCC-02604 |
First Posted: | February 19, 2007 Key Record Dates |
Last Update Posted: | February 12, 2010 |
Last Verified: | February 2010 |
Keywords provided by Fox Chase Cancer Center:
unspecified adult solid tumor, protocol specific |