A New Radiation Therapy Planning System in Patients Undergoing Radiation Therapy for Cancer
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Purpose
RATIONALE: A new radiation therapy planning system may help doctors plan better treatment for patients with cancer.
PURPOSE: This clinical trial is studying a new radiation therapy planning system in patients undergoing radiation therapy for extracranial cancer.
| Condition | Intervention |
|---|---|
|
Unspecified Adult Solid Tumor, Protocol Specific |
Radiation: radiation therapy |
| Study Type: | Interventional |
| Study Design: | Primary Purpose: Treatment |
| Official Title: | Evaluation of the Radionics Body Localizer System and XPLAN/IMRT for Extra-Cranial Sites: A Pilot Study |
| Estimated Enrollment: | 60 |
| Study Start Date: | June 2002 |
| Study Completion Date: | August 2005 |
OBJECTIVES:
- Determine the ability of the Radionics Body System™ to immobilize and re-localize patients receiving radiotherapy to extra-cranial sites of cancer.
- Determine the accuracy of radiation dose calculations for extra-cranial sites of cancer when using the XPLAN™-intensity modulated radiation therapy (XPLAN™/IMRT) integrated software in this system.
OUTLINE: Patients receiving radiotherapy have a Body Localizer cast constructed and undergo a CT scan while immobilized in the Body Localizer. Patients undergo another CT scan in the treatment position using the standard alpha cradle. The XPLAN™-intensity modulated radiation therapy (XPLAN™/IMRT)-generated treatment plan is compared to the standard treatment plan to verify that the calculated dose is within 2-3 percent of the planned dose using standard technique. Patients undergo sets of CT scans 3 additional times over the next few weeks for a total of 8 CT scans Patients may undergo additional CT scans before and after radiotherapy treatments for a maximum of 5 CT scans per week performed over the course of radiotherapy.
PROJECTED ACCRUAL: Approximately 60 patients will be accrued for this study.
Eligibility| Ages Eligible for Study: | Child, Adult, Senior |
| Sexes Eligible for Study: | All |
| Accepts Healthy Volunteers: | No |
DISEASE CHARACTERISTICS:
-
Cancer for which a course of radiotherapy to an extra-cranial site is required
- Head and neck sites excluded
- Initial treatment field (or cone down field) must be no greater than 12 X 10 cm
PATIENT CHARACTERISTICS:
Age
- Not specified
Performance status
- Not specified
Life expectancy
- Not specified
Hematopoietic
- Not specified
Hepatic
- Not specified
Renal
- Not specified
Cardiovascular
- No right heart insufficiency
Other
- Not pregnant or nursing
- Fertile patients must use effective contraception
- Weight must not exceed 150 kilograms (330 pounds)
PRIOR CONCURRENT THERAPY:
Biologic therapy
- Not specified
Chemotherapy
- Not specified
Endocrine therapy
- Not specified
Radiotherapy
- See Disease Characteristics
Surgery
- Not specified
Contacts and LocationsPlease refer to this study by its ClinicalTrials.gov identifier: NCT00436397
| United States, Pennsylvania | |
| Fox Chase Cancer Center - Philadelphia | |
| Philadelphia, Pennsylvania, United States, 19111-2497 | |
| Study Chair: | Steven Seigenberg, MD | Fox Chase Cancer Center |
More Information
| ClinicalTrials.gov Identifier: | NCT00436397 History of Changes |
| Other Study ID Numbers: |
CDR0000304713 P30CA006927 ( US NIH Grant/Contract Award Number ) FCCC-02604 |
| Study First Received: | February 15, 2007 |
| Last Updated: | February 11, 2010 |
Keywords provided by Fox Chase Cancer Center:
|
unspecified adult solid tumor, protocol specific |
ClinicalTrials.gov processed this record on May 25, 2017