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Computed Tomography in Detecting Movement of the Esophagus in Patients Undergoing Radiation Therapy to the Chest

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00433524
First Posted: February 12, 2007
Last Update Posted: February 12, 2010
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborator:
National Cancer Institute (NCI)
Information provided by:
Fox Chase Cancer Center
  Purpose

RATIONALE: Comparing results of diagnostic procedures, such as computed tomography scan (CT scan), done before and after radiation therapy to help detect movement of the esophagus may help doctors plan the best treatment.

PURPOSE: This clinical trial is using CT scan to help detect movement of the esophagus in patients undergoing radiation therapy to the chest.


Condition Intervention
Unspecified Adult Solid Tumor, Protocol Specific Procedure: computed tomography

Study Type: Interventional
Study Design: Primary Purpose: Diagnostic
Official Title: Evaluation of Esophageal Motion by Computed Tomography (CT) During the Course of Thoracic Radiotherapy

Resource links provided by NLM:


Further study details as provided by Fox Chase Cancer Center:

Primary Outcome Measures:
  • Inter- and intra-fraction movement of the esophagus as measured by CT scans

Estimated Enrollment: 30
Study Start Date: April 2003
Study Completion Date: September 2007
Detailed Description:

OBJECTIVES:

  • Determine the inter- and intra-fraction movement of the esophagus using CT scans in patients undergoing thoracic radiotherapy.

OUTLINE: This is a pilot study.

Patients undergo CT scans at baseline and then once weekly during their scheduled radiotherapy sessions to determine esophageal placement while in the treatment position. CT scans are performed before and after the radiotherapy session. Pretreatment and post-treatment scans are compared.

PROJECTED ACCRUAL: A total of 15-30 patients will be accrued for this study.

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

DISEASE CHARACTERISTICS:

  • Planning to undergo definitive thoracic radiotherapy

PATIENT CHARACTERISTICS:

Age

  • Not specified

Performance status

  • Not specified

Life expectancy

  • Not specified

Hematopoietic

  • Not specified

Hepatic

  • Not specified

Renal

  • Not specified

PRIOR CONCURRENT THERAPY:

Biologic therapy

  • Not specified

Chemotherapy

  • Not specified

Endocrine therapy

  • Not specified

Radiotherapy

  • See Disease Characteristics
  • No concurrent palliative thoracic radiotherapy

Surgery

  • Not specified

Other

  • Concurrent participation in other clinical trials allowed
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00433524


Locations
United States, Pennsylvania
Fox Chase Cancer Center - Philadelphia
Philadelphia, Pennsylvania, United States, 19111-2497
Sponsors and Collaborators
Fox Chase Cancer Center
National Cancer Institute (NCI)
Investigators
Study Chair: Andre A. Konski, MD Fox Chase Cancer Center
  More Information

ClinicalTrials.gov Identifier: NCT00433524     History of Changes
Other Study ID Numbers: CDR0000304723
P30CA006927 ( U.S. NIH Grant/Contract )
FCCC-03604
First Submitted: February 8, 2007
First Posted: February 12, 2007
Last Update Posted: February 12, 2010
Last Verified: February 2010

Keywords provided by Fox Chase Cancer Center:
unspecified adult solid tumor, protocol specific