This site became the new on June 19th. Learn more.
Show more Menu IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu IMPORTANT: Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu
Give us feedback

Computed Tomography in Detecting Movement of the Esophagus in Patients Undergoing Radiation Therapy to the Chest

This study has been completed.
National Cancer Institute (NCI)
Information provided by:
Fox Chase Cancer Center Identifier:
First received: February 8, 2007
Last updated: February 11, 2010
Last verified: February 2010

RATIONALE: Comparing results of diagnostic procedures, such as computed tomography scan (CT scan), done before and after radiation therapy to help detect movement of the esophagus may help doctors plan the best treatment.

PURPOSE: This clinical trial is using CT scan to help detect movement of the esophagus in patients undergoing radiation therapy to the chest.

Condition Intervention
Unspecified Adult Solid Tumor, Protocol Specific Procedure: computed tomography

Study Type: Interventional
Study Design: Primary Purpose: Diagnostic
Official Title: Evaluation of Esophageal Motion by Computed Tomography (CT) During the Course of Thoracic Radiotherapy

Resource links provided by NLM:

Further study details as provided by Fox Chase Cancer Center:

Primary Outcome Measures:
  • Inter- and intra-fraction movement of the esophagus as measured by CT scans

Estimated Enrollment: 30
Study Start Date: April 2003
Study Completion Date: September 2007
Detailed Description:


  • Determine the inter- and intra-fraction movement of the esophagus using CT scans in patients undergoing thoracic radiotherapy.

OUTLINE: This is a pilot study.

Patients undergo CT scans at baseline and then once weekly during their scheduled radiotherapy sessions to determine esophageal placement while in the treatment position. CT scans are performed before and after the radiotherapy session. Pretreatment and post-treatment scans are compared.

PROJECTED ACCRUAL: A total of 15-30 patients will be accrued for this study.


Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No


  • Planning to undergo definitive thoracic radiotherapy



  • Not specified

Performance status

  • Not specified

Life expectancy

  • Not specified


  • Not specified


  • Not specified


  • Not specified


Biologic therapy

  • Not specified


  • Not specified

Endocrine therapy

  • Not specified


  • See Disease Characteristics
  • No concurrent palliative thoracic radiotherapy


  • Not specified


  • Concurrent participation in other clinical trials allowed
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00433524

United States, Pennsylvania
Fox Chase Cancer Center - Philadelphia
Philadelphia, Pennsylvania, United States, 19111-2497
Sponsors and Collaborators
Fox Chase Cancer Center
National Cancer Institute (NCI)
Study Chair: Andre A. Konski, MD Fox Chase Cancer Center
  More Information Identifier: NCT00433524     History of Changes
Other Study ID Numbers: CDR0000304723
P30CA006927 ( U.S. NIH Grant/Contract )
Study First Received: February 8, 2007
Last Updated: February 11, 2010

Keywords provided by Fox Chase Cancer Center:
unspecified adult solid tumor, protocol specific processed this record on August 23, 2017