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Saline Instillation Before Tracheal Suctioning and the Incidence of Ventilator Associated Pneumonia

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ClinicalTrials.gov Identifier: NCT00432718
Recruitment Status : Completed
First Posted : February 8, 2007
Last Update Posted : February 8, 2007
Sponsor:
Information provided by:
Hospital do Cancer, Sao Paulo

Brief Summary:
Compare the incidence of ventilator associated pneumonia with or without tracheal isotonic saline instillation before tracheal suctioning

Condition or disease Intervention/treatment
Mechanical Ventilation Critically Ill Patients Procedure: Saline Instillation before Tracheal Suctioning

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 260 participants
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: Single
Primary Purpose: Prevention
Study Start Date : August 2001

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Pneumonia
U.S. FDA Resources




Primary Outcome Measures :
  1. incidence of ventilator associated pneumonia

Secondary Outcome Measures :
  1. atelectasis
  2. tube occlusion


Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Consecutive patients foreseen to receive mechanical ventilation for more than 72 hours

Exclusion Criteria:

  • Previous mechanical ventilation in the last month
  • Mechanical ventilation for more than 6 hours before arrival at ICU,
  • Contraindication to bronchoscopy and
  • Be expected to die or undergo withdrawal treatment within 48 hours-

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00432718


Locations
Brazil
ICU Hospital do Câncer
Sao Paulo, SP, Brazil, 01509-010
Sponsors and Collaborators
Hospital do Cancer, Sao Paulo
Investigators
Principal Investigator: Pedro Caruso, MD Intensive Care Unit - Hospital do Câncer and University of Sao Paulo Medical School

ClinicalTrials.gov Identifier: NCT00432718     History of Changes
Other Study ID Numbers: 342/01
First Posted: February 8, 2007    Key Record Dates
Last Update Posted: February 8, 2007
Last Verified: February 2007

Keywords provided by Hospital do Cancer, Sao Paulo:
Pneumonia
Ventilator Associated Pneumonia
Prevention

Additional relevant MeSH terms:
Pneumonia
Critical Illness
Pneumonia, Ventilator-Associated
Lung Diseases
Respiratory Tract Diseases
Respiratory Tract Infections
Disease Attributes
Pathologic Processes
Cross Infection
Infection
Ventilator-Induced Lung Injury
Lung Injury