Saline Instillation Before Tracheal Suctioning and the Incidence of Ventilator Associated Pneumonia

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00432718
Recruitment Status : Completed
First Posted : February 8, 2007
Last Update Posted : February 8, 2007
Information provided by:
Hospital do Cancer, Sao Paulo

Brief Summary:
Compare the incidence of ventilator associated pneumonia with or without tracheal isotonic saline instillation before tracheal suctioning

Condition or disease Intervention/treatment Phase
Mechanical Ventilation Critically Ill Patients Procedure: Saline Instillation before Tracheal Suctioning Not Applicable

Study Type : Interventional  (Clinical Trial)
Enrollment : 260 participants
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: Single
Primary Purpose: Prevention
Study Start Date : August 2001

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Pneumonia

Primary Outcome Measures :
  1. incidence of ventilator associated pneumonia

Secondary Outcome Measures :
  1. atelectasis
  2. tube occlusion

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Consecutive patients foreseen to receive mechanical ventilation for more than 72 hours

Exclusion Criteria:

  • Previous mechanical ventilation in the last month
  • Mechanical ventilation for more than 6 hours before arrival at ICU,
  • Contraindication to bronchoscopy and
  • Be expected to die or undergo withdrawal treatment within 48 hours-

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00432718

ICU Hospital do Câncer
Sao Paulo, SP, Brazil, 01509-010
Sponsors and Collaborators
Hospital do Cancer, Sao Paulo
Principal Investigator: Pedro Caruso, MD Intensive Care Unit - Hospital do Câncer and University of Sao Paulo Medical School Identifier: NCT00432718     History of Changes
Other Study ID Numbers: 342/01
First Posted: February 8, 2007    Key Record Dates
Last Update Posted: February 8, 2007
Last Verified: February 2007

Keywords provided by Hospital do Cancer, Sao Paulo:
Ventilator Associated Pneumonia

Additional relevant MeSH terms:
Critical Illness
Pneumonia, Ventilator-Associated
Lung Diseases
Respiratory Tract Diseases
Respiratory Tract Infections
Disease Attributes
Pathologic Processes
Cross Infection
Ventilator-Induced Lung Injury
Lung Injury