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Usefulness of 64 Slice Multi-Detector Computed Tomography as a First Diagnostic Approach in Acute Chest Pain Patients

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT00431886
Recruitment Status : Completed
First Posted : February 6, 2007
Last Update Posted : June 21, 2011
Sponsor:
Information provided by:
Seoul National University Bundang Hospital

Brief Summary:
The purpose of this study is to determine the usefulness of 64 slice multi-detector computed tomography as a first diagnostic approach in acute chest pain patients in emergency room

Condition or disease Intervention/treatment
Chest Pains Procedure: 64 multi-detector computed tomography

Detailed Description:
We prospectively enrolled the patients with acute chest pain who visited ED. Exclusion criteria were myocardial infarction (MI) with ST elevation, unstable vital sign, uncontrolled arrhythmia, renal dysfunction, hypersensitivity to contrast media and pregnancy. Patients were allocated into 3 categories based on history, physical exam, and electrocardiogram: 1) definite angina with uncertainty of regarding MI (high risk), 2) probable angina (intermediate risk), 3) low likelihood of angina (low risk), and then randomized to either receive MDCT immediately (MDCT group), or not (control). We compared diagnostic accuracy, length of stay in ER, admission rate, and major adverse cardiac events (MACE) and clinical diagnosis in 1 month after discharge from ED.

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 400 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
Official Title: Usefulness of 64 Slice Multi-Detector Computed Tomography as a First Diagnostic Approach in Acute Chest Pain Patients
Study Start Date : April 2006
Study Completion Date : December 2007

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U.S. FDA Resources




Primary Outcome Measures :
  1. Admission rate
  2. Unnecessary admission rate

Secondary Outcome Measures :
  1. Stay time in emergency department
  2. Diagnostic accuracy
  3. MACE


Information from the National Library of Medicine

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Ages Eligible for Study:   19 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Acute chest pain patient visiting emergency room

Exclusion Criteria:

  • unstable vital sign
  • renal failure
  • ST elevation myocardial infarction
  • uncontrolled arrhythmia
  • hypersensitivity to contrast dye
  • clinically no possibility of angina

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00431886


Locations
Korea, Republic of
Seoul National University Bundang hospital
Sungnam-si, Kyungkido, Korea, Republic of, 463-707
Sponsors and Collaborators
Seoul National University Bundang Hospital
Investigators
Study Director: Huk-Jae Chang, MD Seoul National University Bundang Hospital

ClinicalTrials.gov Identifier: NCT00431886     History of Changes
Other Study ID Numbers: B-0603/031-009
First Posted: February 6, 2007    Key Record Dates
Last Update Posted: June 21, 2011
Last Verified: February 2007

Keywords provided by Seoul National University Bundang Hospital:
Chest pains
Computed tomography
Emergency

Additional relevant MeSH terms:
Chest Pain
Pain
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms