Clinical and Economic Impact of Interventions by a Clinical Pharmacist on Antibiotic Use on Surgical Wards
|ClinicalTrials.gov Identifier: NCT00431483|
Recruitment Status : Completed
First Posted : February 5, 2007
Last Update Posted : September 26, 2013
|Condition or disease||Intervention/treatment||Phase|
|Bacterial Infections||Behavioral: pharmaceutical consulting||Not Applicable|
Inappropriate or incorrect use of antibacterials exerts selection pressure on pathogens potentiating emergence of resistance, puts patients at risk for unnecessary adverse drug reactions and potentially prolongs the length of stay in hospital thus increasing healthcare costs.
In an effort to improve the quality of antibiotic drug therapy on surgical wards of a large university hospital, specific consulting by a clinical pharmacist was established.
The objective of this study is to assess the impact of pharmaceutical consulting on the quality and costs of antibiotic use in surgical wards.
Within a control period the current pattern of antibiotic use is monitored. During the intervention period, the impact of the interventions made by the clinical pharmacist on antibiotic use is examined. One ward serves as a parallel control group; no intervention is being made on this ward throughout this study.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||779 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Primary Purpose:||Health Services Research|
|Official Title:||Clinical and Economic Impact of Interventions by a Clinical Pharmacist on Antibiotic Use on Surgical Wards|
|Study Start Date :||February 2007|
|Actual Primary Completion Date :||February 2008|
|Actual Study Completion Date :||February 2008|
Behavioral: pharmaceutical consulting
to measure if information and advice by a pharmacist has an impact on quality and quantity of prescribed antibacterials
- overall duration of antibiotic therapy during study period [ Time Frame: Feb 2008 ]
- iv to oral switch [ Time Frame: Feb 2008 ]number of courses of iv antibiotics switched to oral antibiotics; duration of iv treatment
- compliance of treatment with hospital formulary for antibiotic therapy [ Time Frame: Feb 2008 ]
- cost of antibiotic therapy [ Time Frame: Feb 2008 ]
- number and duration of therapy with antibiotics with redundant spectra [ Time Frame: Feb 2008 ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00431483
|Luwig Maximilians University - Klinikum Grosshadern|
|Munich, Bavaria, Germany, 81377|
|Study Director:||Karl-Walter Jauch, Prof. Dr.||Klinikum Grosshadern|