Clinical and Economic Impact of Interventions by a Clinical Pharmacist on Antibiotic Use on Surgical Wards
The purpose of this study is to establish the impact of a pharmacist's recommendations regarding choice, dosing and duration of antibiotic therapy on quality and cost of antibiotic treatment on surgical wards.
|Study Design:||Allocation: Non-Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Health Services Research
|Official Title:||Clinical and Economic Impact of Interventions by a Clinical Pharmacist on Antibiotic Use on Surgical Wards|
- overall duration of antibiotic therapy during study period [ Time Frame: Feb 2008 ] [ Designated as safety issue: No ]
- iv to oral switch [ Time Frame: Feb 2008 ] [ Designated as safety issue: No ]number of courses of iv antibiotics switched to oral antibiotics; duration of iv treatment
- compliance of treatment with hospital formulary for antibiotic therapy [ Time Frame: Feb 2008 ] [ Designated as safety issue: No ]
- cost of antibiotic therapy [ Time Frame: Feb 2008 ] [ Designated as safety issue: No ]
- number and duration of therapy with antibiotics with redundant spectra [ Time Frame: Feb 2008 ] [ Designated as safety issue: No ]
|Study Start Date:||February 2007|
|Study Completion Date:||February 2008|
|Primary Completion Date:||February 2008 (Final data collection date for primary outcome measure)|
Behavioral: pharmaceutical consulting
to measure if information and advice by a pharmacist has an impact on quality and quantity of prescribed antibacterials
Inappropriate or incorrect use of antibacterials exerts selection pressure on pathogens potentiating emergence of resistance, puts patients at risk for unnecessary adverse drug reactions and potentially prolongs the length of stay in hospital thus increasing healthcare costs.
In an effort to improve the quality of antibiotic drug therapy on surgical wards of a large university hospital, specific consulting by a clinical pharmacist was established.
The objective of this study is to assess the impact of pharmaceutical consulting on the quality and costs of antibiotic use in surgical wards.
Within a control period the current pattern of antibiotic use is monitored. During the intervention period, the impact of the interventions made by the clinical pharmacist on antibiotic use is examined. One ward serves as a parallel control group; no intervention is being made on this ward throughout this study.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00431483
|Luwig Maximilians University - Klinikum Grosshadern|
|Munich, Bavaria, Germany, 81377|
|Study Director:||Karl-Walter Jauch, Prof. Dr.||Klinikum Grosshadern|