Diabetes Genome Project: A Prospective Registry to Identify Genetic Variation Among Diabetic Patients (DGP)
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|ClinicalTrials.gov Identifier: NCT00428961|
Recruitment Status : Completed
First Posted : January 30, 2007
Last Update Posted : January 10, 2013
Previous scientific research has found multiple genes that affect the risk for developing heart disease or complications during the treatment of heart disease. Less is currently known about how patients with heart disease may differ on the basis of other ailments they may have and how these other ailments may affect their treatment and prognosis. For this reason, researchers at the Mid America Heart Institute are conducting this research to find out how genes affect heart disease and recovery following angioplasty. The study will include patients with diabetes in order to determine if their genes are different from patients without diabetes.
A total of 1,607 patients were enrolled. There were 2 groups of patients selected for this study. The first group of patients included into the study will be those that are scheduled to have a diagnostic angiogram only. The second group of patients were those that had along with the angiogram a percutaneous transluminal coronary angioplasty, PTCA and or the use of a device called a coronary "stent", designed to help prop open the artery and to help avoid collapse. Samples for both groups will be stored for 30 years. After this time, all samples will be destroyed. Ultimately, we are hopeful that we will identify genes that will identify groups of patients at risk for heart disease.
|Condition or disease|
|Diabetes Mellitus Insulin Resistance Atherosclerosis|
|Study Type :||Observational|
|Actual Enrollment :||1607 participants|
|Official Title:||Diabetic Genome Project: A Multi-Phase Prospective Registry to Identify Genetic Variation Among Diabetic Patients Undergoing Coronary Revascularization|
|Study Start Date :||July 2002|
|Actual Primary Completion Date :||July 2008|
|Actual Study Completion Date :||July 2008|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00428961
|United States, Missouri|
|Saint Luke's Hospital Mid America Heart Institute|
|Kansas City, Missouri, United States, 64111|
|Principal Investigator:||Steven P Marso, MD||University of Missouri Kansas City, Saint Luke's Hospital|