Effect of Postoperative Laxative on Bowel Function After Colonic Surgery

This study has been completed.

Sponsor:

Information provided by:

Hvidovre University Hospital

ClinicalTrials.gov Identifier:

NCT00427492

First received: January 26, 2007

Last updated: February 10, 2009

Last verified: February 2009

History of Changes

Purpose

Randomised doublet blinded study of the effect of tablet Magnesia (laxative) on post operative bowel ileus after open colonic resection. Material: 56 patients in two equal groups. Primary endpoint: Bowel function. Secondary endpoints: Intake of food and drinks.

Condition	Intervention	Phase
Colonic Cancer	Drug: Magnesia Drug: Placebo	Phase 4


Study Type:	Interventional
Study Design:	Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double Blind (Participant, Investigator) Primary Purpose: Supportive Care
Official Title:	Effect of Postoperative Laxative on Bowel Function After Colonic Surgery

Resource links provided by NLM:

MedlinePlus related topics: Bowel Movement

Drug Information available for: Magnesium oxide

U.S. FDA Resources

Further study details as provided by Hvidovre University Hospital:

Primary Outcome Measures:

Time to defecation after colonic resection [ Time Frame: 2-8 days ]


Enrollment:	56
Study Start Date:	January 2007
Study Completion Date:	January 2009
Primary Completion Date:	January 2009 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
Active Comparator: Magnesia Medical laxative	Drug: Magnesia Tablet magnesia 500mg. 2 tablet 2 times a day for a week Drug: Placebo
Placebo Comparator: Placebo Placebo	Drug: Placebo

Eligibility


Ages Eligible for Study:	18 Years and older (Adult, Senior)
Sexes Eligible for Study:	All

Criteria

Inclusion Criteria:

Patients with planned elective colonic resection

Exclusion Criteria:

Previous extended abdominal surgery
Pregnancy
Opioid or alcohol abuse

Contacts and Locations

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00427492

Locations


Denmark
Copenhagen University hospital Hvidovre
Hvidovre, Denmark, 2650

Sponsors and Collaborators

Hvidovre University Hospital

Investigators


Principal Investigator:	Jens Andersen, MD	Copenhagen University Hospital, Hvidovre

More Information


Responsible Party:	Jens Andersen. Consultant Surgeon, Copenhagen University Hospital - Hvidovre
ClinicalTrials.gov Identifier:	NCT00427492 History of Changes
Other Study ID Numbers:	02 290964
Study First Received:	January 26, 2007
Last Updated:	February 10, 2009

Additional relevant MeSH terms:


Colonic Neoplasms Colorectal Neoplasms Intestinal Neoplasms Gastrointestinal Neoplasms Digestive System Neoplasms Neoplasms by Site Neoplasms Digestive System Diseases Gastrointestinal Diseases	Colonic Diseases Intestinal Diseases Laxatives Cathartics Magnesium Oxide Gastrointestinal Agents Antacids Molecular Mechanisms of Pharmacological Action

ClinicalTrials.gov processed this record on June 27, 2017

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