Urinary Excretion of Enteroviruses From Children With a Presumed Enteroviral Infection
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|ClinicalTrials.gov Identifier: NCT00426699|
Recruitment Status : Completed
First Posted : January 25, 2007
Last Update Posted : May 19, 2011
|Condition or disease|
Enteroviruses have been shown to cause mesangioproliferation and glomerulonephritis in mice (especially coxsackievirus B4). In some cases, large amounts of IgA are deposited in the mesangium, resembling human IgA-nephropathy. In humans, case reports indicate the propensity of certain enteroviruses to cause kidney infections.
Our project aims to analyze urine of children with suspected enteroviral infections (e.g. meningitis, myocarditis, sepsis of the newborn etc.) to identify cases suspicious of concomitant enteroviral kidney affection. To achieve this aim, enterovirus-PCRs will be performed and microhematuria searched for.
|Study Type :||Observational|
|Actual Enrollment :||82 participants|
|Study Start Date :||June 2006|
|Actual Primary Completion Date :||November 2008|
|Actual Study Completion Date :||November 2008|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00426699
|Dept. Nephrology & Hypertension, Univ. Hospital Bern|
|Bern, Switzerland, 3010|
|Principal Investigator:||Andreas Pasch, MD||University of Bern|