Airway Responses to Montelukast and Desloratadine.
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Montelukast (for asthma) and desloratadine (for allergies) are effective therapy for their current uses. Part of what happens when your allergies trigger your asthma should be prevented by either of these drugs. This project is being conducted to determine if these drugs are effective, either alone or in combination, on controlling asthma that is triggered by allergies.
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Ages Eligible for Study:
18 Years and older (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
baseline FEV1 > or = 65% predicted
positive methacholine challenge (i.e. methacholine PC20 < or = 16mg/ml