Perioperative Chemoradiotherapy for Potentially Resectable Gastric Cancer
Recruitment status was: Recruiting
Rationale: Adjuvant chemoradiation considered as standard of care after curative surgery for adenocarcinoma of stomach and gastroesophageal cancer. Preoperative chemotherapy in the in locally advanced gastric cancer results in significant tumoral downstaging with improved rate of curative resections.
Purpose: To evaluate feasibility and safety of combination of preoperative chemotherapy and postoperative chemoradiation for locally advanced adenocarcinoma of stomach and gastroesophageal cancer
|Stomach Neoplasms||Procedure: Chemotherapy Procedure: surgery Procedure: radiotherapy||Phase 2|
|Study Design:||Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:||Phase II Study of Preoperative Chemotherapy and Postoperative Chemo-Radiation for Newly Diagnosed, Potentially Resectable Gastric Cancer|
- Feasibility of the study regimen.
- Rate of R0 resection following chemotherapy.
- Morbidity and mortality of surgery following chemotherapy.
- Overall and progression free survival following the study treatment plan
|Study Start Date:||April 2007|
Please refer to this study by its ClinicalTrials.gov identifier: NCT00420394
|Contact: Margarita Tokar, MD||+972-8-6400768||Ritato@clalit.org.il|
|Contact: Dmitri Bobilev, MDemail@example.com|
|Soroka University Medical Center,Oncology Center||Recruiting|
|Contact: margarita Tokar, MD +972-86400768 firstname.lastname@example.org|
|Sub-Investigator: Konstantin Lavrenkov, MD|
|Study Chair:||Margarita Tokar, MD||Soroka University Medical Center and Ben-Gurion University of the Negev|