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Proteomic Analysis of HLA Complex in Solid Cancers: Breast, Ovary, Colon, Rectum, Stomach, and Pancreas

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified January 2007 by Hillel Yaffe Medical Center.
Recruitment status was:  Not yet recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT00419627
First Posted: January 8, 2007
Last Update Posted: January 8, 2007
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborator:
Technion, Israel Institute of Technology
Information provided by:
Hillel Yaffe Medical Center
  Purpose
The purpose of this study is to evaluate the presence of proteins in solid tumors which may lead to an immune response

Condition
Colorectal Neoplasms Stomach Neoplasms Pancreatic Neoplasms Breast Neoplasms Ovarian Cancer

Study Type: Observational
Study Design: Observational Model: Natural History
Time Perspective: Longitudinal
Time Perspective: Prospective
Official Title: Proteomic Analysis of Serology and Peptides Presented on the HLA Complex of Breast, Ovarian, Colon, Rectal, Gastric and Pancreatic Adenocarcinoma.

Resource links provided by NLM:


Further study details as provided by Hillel Yaffe Medical Center:

Estimated Enrollment: 160
Study Start Date: February 2007
Detailed Description:
The main objective of the study is to evaluate which proteins are presented by the HLA complex of solid tumors. Secondary objectives include to evaluate whether an immune response specific to these proteins has actually been provoked and whether there is a similar immune response following recurrence. Real specimens will be evaluated using PCR and mass spectrometry.
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Criteria

Inclusion Criteria:

  • Patients with adenocarcinoma of breast, colon, rectum, ovary , stomach, pancreas

Exclusion Criteria:

  • Withdrawal of consent
  • Small specimen which does not allow to retrieve tissue without interfering with pathologic evaluation
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00419627


Contacts
Contact: Itamar Ashkenazi, M.D. 972-4-6304761 i_ashkenazi@yahoo.com

Locations
Israel
Hillel Yaffe Medical Center Not yet recruiting
Hadera, Israel, 38100
Contact: Itamar Ashkenazi, M.D.    972-4-6304761    i_ashkenazi@yahoo.com   
Sponsors and Collaborators
Hillel Yaffe Medical Center
Technion, Israel Institute of Technology
Investigators
Principal Investigator: Itamar Ashkenazi, M.D. Hillel Yaffe Medical Center
  More Information

ClinicalTrials.gov Identifier: NCT00419627     History of Changes
Other Study ID Numbers: ProtHYMC
First Submitted: January 5, 2007
First Posted: January 8, 2007
Last Update Posted: January 8, 2007
Last Verified: January 2007

Keywords provided by Hillel Yaffe Medical Center:
proteomics of solid tumors

Additional relevant MeSH terms:
Neoplasms
Breast Neoplasms
Colorectal Neoplasms
Pancreatic Neoplasms
Stomach Neoplasms
Neoplasms by Site
Breast Diseases
Skin Diseases
Intestinal Neoplasms
Gastrointestinal Neoplasms
Digestive System Neoplasms
Digestive System Diseases
Gastrointestinal Diseases
Colonic Diseases
Intestinal Diseases
Rectal Diseases
Endocrine Gland Neoplasms
Pancreatic Diseases
Endocrine System Diseases
Stomach Diseases