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Proteomic Analysis of HLA Complex in Solid Cancers: Breast, Ovary, Colon, Rectum, Stomach, and Pancreas

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified January 2007 by Hillel Yaffe Medical Center.
Recruitment status was:  Not yet recruiting
Technion, Israel Institute of Technology
Information provided by:
Hillel Yaffe Medical Center Identifier:
First received: January 5, 2007
Last updated: NA
Last verified: January 2007
History: No changes posted
The purpose of this study is to evaluate the presence of proteins in solid tumors which may lead to an immune response

Colorectal Neoplasms Stomach Neoplasms Pancreatic Neoplasms Breast Neoplasms Ovarian Cancer

Study Type: Observational
Study Design: Observational Model: Natural History
Time Perspective: Longitudinal
Time Perspective: Prospective
Official Title: Proteomic Analysis of Serology and Peptides Presented on the HLA Complex of Breast, Ovarian, Colon, Rectal, Gastric and Pancreatic Adenocarcinoma.

Resource links provided by NLM:

Further study details as provided by Hillel Yaffe Medical Center:

Estimated Enrollment: 160
Study Start Date: February 2007
Detailed Description:
The main objective of the study is to evaluate which proteins are presented by the HLA complex of solid tumors. Secondary objectives include to evaluate whether an immune response specific to these proteins has actually been provoked and whether there is a similar immune response following recurrence. Real specimens will be evaluated using PCR and mass spectrometry.

Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All

Inclusion Criteria:

  • Patients with adenocarcinoma of breast, colon, rectum, ovary , stomach, pancreas

Exclusion Criteria:

  • Withdrawal of consent
  • Small specimen which does not allow to retrieve tissue without interfering with pathologic evaluation
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00419627

Contact: Itamar Ashkenazi, M.D. 972-4-6304761

Hillel Yaffe Medical Center Not yet recruiting
Hadera, Israel, 38100
Contact: Itamar Ashkenazi, M.D.    972-4-6304761   
Sponsors and Collaborators
Hillel Yaffe Medical Center
Technion, Israel Institute of Technology
Principal Investigator: Itamar Ashkenazi, M.D. Hillel Yaffe Medical Center
  More Information Identifier: NCT00419627     History of Changes
Other Study ID Numbers: ProtHYMC
Study First Received: January 5, 2007
Last Updated: January 5, 2007

Keywords provided by Hillel Yaffe Medical Center:
proteomics of solid tumors

Additional relevant MeSH terms:
Breast Neoplasms
Colorectal Neoplasms
Pancreatic Neoplasms
Stomach Neoplasms
Neoplasms by Site
Breast Diseases
Skin Diseases
Intestinal Neoplasms
Gastrointestinal Neoplasms
Digestive System Neoplasms
Digestive System Diseases
Gastrointestinal Diseases
Colonic Diseases
Intestinal Diseases
Rectal Diseases
Endocrine Gland Neoplasms
Pancreatic Diseases
Endocrine System Diseases
Stomach Diseases processed this record on September 20, 2017