Proteomic Analysis of HLA Complex in Solid Cancers: Breast, Ovary, Colon, Rectum, Stomach, and Pancreas

The recruitment status of this study is unknown because the information has not been verified recently.
Verified January 2007 by Hillel Yaffe Medical Center.
Recruitment status was  Not yet recruiting
Technion, Israel Institute of Technology
Information provided by:
Hillel Yaffe Medical Center Identifier:
First received: January 5, 2007
Last updated: NA
Last verified: January 2007
History: No changes posted
The purpose of this study is to evaluate the presence of proteins in solid tumors which may lead to an immune response

Colorectal Neoplasms
Stomach Neoplasms
Pancreatic Neoplasms
Breast Neoplasms
Ovarian Cancer

Study Type: Observational
Study Design: Observational Model: Natural History
Time Perspective: Longitudinal
Official Title: Proteomic Analysis of Serology and Peptides Presented on the HLA Complex of Breast, Ovarian, Colon, Rectal, Gastric and Pancreatic Adenocarcinoma.

Resource links provided by NLM:

Further study details as provided by Hillel Yaffe Medical Center:

Estimated Enrollment: 160
Study Start Date: February 2007
Detailed Description:
The main objective of the study is to evaluate which proteins are presented by the HLA complex of solid tumors. Secondary objectives include to evaluate whether an immune response specific to these proteins has actually been provoked and whether there is a similar immune response following recurrence. Real specimens will be evaluated using PCR and mass spectrometry.

Genders Eligible for Study:   Both

Inclusion Criteria:

  • Patients with adenocarcinoma of breast, colon, rectum, ovary , stomach, pancreas

Exclusion Criteria:

  • Withdrawal of consent
  • Small specimen which does not allow to retrieve tissue without interfering with pathologic evaluation
  Contacts and Locations
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Please refer to this study by its identifier: NCT00419627

Contact: Itamar Ashkenazi, M.D. 972-4-6304761

Hillel Yaffe Medical Center Not yet recruiting
Hadera, Israel, 38100
Contact: Itamar Ashkenazi, M.D.    972-4-6304761   
Sponsors and Collaborators
Hillel Yaffe Medical Center
Technion, Israel Institute of Technology
Principal Investigator: Itamar Ashkenazi, M.D. Hillel Yaffe Medical Center
  More Information Identifier: NCT00419627     History of Changes
Other Study ID Numbers: ProtHYMC 
Study First Received: January 5, 2007
Last Updated: January 5, 2007
Health Authority: Israel: Ethics Commission

Keywords provided by Hillel Yaffe Medical Center:
proteomics of solid tumors

Additional relevant MeSH terms:
Breast Neoplasms
Colorectal Neoplasms
Pancreatic Neoplasms
Stomach Neoplasms
Breast Diseases
Colonic Diseases
Digestive System Diseases
Digestive System Neoplasms
Endocrine Gland Neoplasms
Endocrine System Diseases
Gastrointestinal Diseases
Gastrointestinal Neoplasms
Intestinal Diseases
Intestinal Neoplasms
Neoplasms by Site
Pancreatic Diseases
Rectal Diseases
Skin Diseases
Stomach Diseases processed this record on May 26, 2016