The Impact of Right Ventricular Pacing on Tricuspid Regurgitation
Recruitment status was Recruiting
"1" To examine whether right ventricular pacing has an impact on tricuspid regurgitation grade that is related to pacing rather than to valve closure interference by the electrode.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Study Start Date:||March 2007|
|Estimated Study Completion Date:||March 2010|
|Estimated Primary Completion Date:||March 2010 (Final data collection date for primary outcome measure)|
"1" Traditionally, tricuspid regurgitation in the presence of pacemaker is attributed to the physical interference of the valve closure by the electrode.
"2" Right ventricular pacing may be associated with dyssynchrony in contraction of the right ventricular wall (i.e. septum and free wall.
"3" The tricuspid sub-valvar apparatus is anchored to the septum and free wall, thus may be sensitive to dyssynchrony in those wals contraction.
"4" The study hypothesis is that the dyssynchrony in right ventricular contraction, induced by pacing, may increase tricuspid regurgitation grade and that this is a mechanism is independent of the mechanical effect of the electrode on the valve closure.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00419354
|Contact: Mordehay Vaturi, MDfirstname.lastname@example.org|
|Rabin Medical Center||Recruiting|
|Petach Tikva, Israel, 49100|
|Contact: Mordehay Vaturi, MD 97239376176 email@example.com|
|Principal Investigator: Mordehay Vaturi, MD|
|Principal Investigator:||Mordehay Vaturi, MD||Department of Cardiology, Rabin Medical Center|