A Study on the Effect of Kidney Disease on a Diabetes Medication (0431-008)
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.
Read our disclaimer for details.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Layout table for eligibility information
Ages Eligible for Study:
18 Years to 75 Years (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Inclusion Criteria :
Male and non-pregnant females with a clinical diagnosis of renal insufficiency with mild, moderate, severe or end stage renal disease on hemodialysis
A body mass index of less than 40 kg per meter squared (body weight in kg divided by height in meters squared)
Smokes less than 10 cigarettes/day
Exclusion Criteria :
Patients with uncontrolled diabetes or uncontrolled congestive heart failure
Patient has abnormal prestudy laboratory measurements including serum potassium or white blood counts
Patient has systolic blood pressure below 100 mm Hg or above 180 mm Hg
Patient has diastolic blood pressure less than 50 mm Hg systolic or above 100 mmHg