Total Knee Arthroplasty: Comparison of Fixed and Mobile Bearings

This study is ongoing, but not recruiting participants.
Information provided by (Responsible Party):
Brigitte Jolles, MD, University of Lausanne Hospitals Identifier:
First received: January 3, 2007
Last updated: November 10, 2014
Last verified: November 2014

The goal of this study is to provide gait parameters as a new objective method to assess total knee arthroplasty outcome between patients with fixed- and mobile-bearing, using an ambulatory device with minimal sensor configuration.

Condition Intervention Phase
Knee Osteoarthritis
Device: Total knee arthroplasty: mobile bearing
Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Total Knee Arthroplasty: Comparison of Fixed and Mobile Bearings

Resource links provided by NLM:

Further study details as provided by University of Lausanne Hospitals:

Primary Outcome Measures:
  • Gait [ Time Frame: Pre-op;1year;5years;10years ] [ Designated as safety issue: No ]
  • Subjective evaluation EQ-5D; WOMAC, VAS pain [ Time Frame: Pre-op;1year;5years;10years ] [ Designated as safety issue: No ]
  • Semi-objective evaluation KSS clinical and radiological [ Time Frame: Pre-op;1year;5years;10years ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Dislocation [ Time Frame: Pre-op;1year;5years;10years ] [ Designated as safety issue: No ]

Enrollment: 64
Study Start Date: February 2004
Estimated Primary Completion Date: November 2015 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: TKA
Device: Total knee arthroplasty: mobile bearing
Total knee arthroplasty: mobile bearing


Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Patients suffering from a primary unilateral knee osteoarthritis and requiring a knee replacement
  • Informed consent
  Contacts and Locations
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Please refer to this study by its identifier: NCT00417859

Lausanne, Switzerland
Sponsors and Collaborators
University of Lausanne Hospitals
Principal Investigator: B Jolles, MD MSc HOSR
  More Information

No publications provided

Responsible Party: Brigitte Jolles, MD, Prof, University of Lausanne Hospitals Identifier: NCT00417859     History of Changes
Other Study ID Numbers: HO 218/01
Study First Received: January 3, 2007
Last Updated: November 10, 2014
Health Authority: Switzerland: Institutional Review Board processed this record on March 30, 2015