Use of Intravitreal Bevacizumab in Patients With Diffuse Diabetic Macular Edema
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ClinicalTrials.gov Identifier: NCT00417716
Recruitment Status : Unknown
Verified June 2006 by Asociación para Evitar la Ceguera en México. Recruitment status was: Active, not recruiting
Intravitreal Bevacizumab is an effective treatment for the diffuse diabetic macular edema
Condition or disease
Diabetes Mellitus Type 2Diabetic Macular Edema
Drug: Intravitreal Bevacizumab
A non-randomized prospective clinical interventional study which includes 45 non previously treated patients with DME. The patients received a single intravitreal injection of 2.5 mg bevacizumab. Follow-up included clinical examination (best corrected visual acuity (BCVA, intraocular pressure (IOP), cataract grading, DME characteristics and systemic check-up) pre-injection, at first visit, at weeks 1 and 2 and months 1 and 3. OCT and fluorescein angiography was evaluated at months 1 and 3.
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Ages Eligible for Study:
45 Years and older (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Type 2 diabetes
Macular edema involving the center of the macula demonstrated on OCT
Clear ocular media
Older than 45 years
BCVA of the fellow eye at least 20/100
Renal diabetic disease, uncontrolled hypertension or stroke history
Other ocular disease
Ocular surgery excepting uncomplicated phacoemulsification
History of photocoagulation (panretinal or focal)
History of another intravitreal treatment (like triamcinolone)