Biventricular Pacing After Coronary Artery Bypass Grafting (BIVAC)
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The purpose of this study is to determine which pacing mode after coronary artery bypass grafting in patients with reduced left ventricular function is hemodynamically favorable.
Condition or disease
Cardiac Pacing,ArtificialCoronary Artery BypassVentricular Function, Left
Procedure: Postoperative Pacing
Patients with severely reduced left ventricular function undergoing coronary artery bypass grafting (CABG) are at an increased perioperative risk and often need prolonged postoperative treatment on intensive care units. A significant portion of these patients require postoperative pacing. Right ventricular pacing has been shown to be hemodynamically deleterious whereas biventricular pacing improves cardiac output in patients with severely reduced left ventricular function and bundle branch block. The purpose of this study is to compare DDD-right ventricular, DDD-biventricular and AAI pacing in CABG patients with an ejection fraction less than 40% in a prospective randomized setting.
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Ages Eligible for Study:
18 Years and older (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Elective or urgent coronary artery bypass grafting
Preoperative ejection fraction less than 40%
Existing permanent pacemaker or ICD
Concomitant valve surgery
Preoperative cardiovascular instability requiring intubation or IABP use