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Factors Associated With Coronary Heart Disease in African Americans in the Jackson Heart Study

This study has been completed.
Information provided by:
National Heart, Lung, and Blood Institute (NHLBI) Identifier:
First received: December 20, 2006
Last updated: July 28, 2016
Last verified: December 2006
Coronary heart disease (CHD) is the leading cause of deaths that are related to cardiovascular disease in the United States, and Mississippi's CHD mortality rate is the highest in the nation. This study will examine data from the Jackson Heart Study to determine the effect of socioeconomic status and psychosocial factors on CHD risk in African Americans in Mississippi.

Cardiovascular Diseases
Coronary Disease

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Disparities in CHD in the Jackson Heart Study

Resource links provided by NLM:

Further study details as provided by National Heart, Lung, and Blood Institute (NHLBI):

Estimated Enrollment: 5302
Study Start Date: September 2000
Study Completion Date: March 2004
Detailed Description:

CHD is a disease that is characterized by narrowing of the coronary arteries that supply blood to the heart. As a result, insufficient amounts of oxygen and nutrients reach the heart, which can cause chest pain or heart attack. Studies have shown that people's socioeconomic status is associated with their health, and that African Americans experience the highest rates of heart disease in the U.S. The Jackson Heart Study (JHS) is currently being conducted in Jackson, Mississippi, and is studying the factors that influence the development of cardiovascular disease in African American men and women. This study will examine data from the JHS to determine the effect of socioeconomic status and psychosocial factors on CHD risk in African Americans in Mississippi.

This study will recruit participants from the JHS only. Participants will report to the study site at least once for 4.5 hours for baseline measurements. Visits will include measurements of body size and blood pressure, an electrocardiogram, an echocardiogram, an ultrasound of the carotid artery, blood and urine collection, a lung function test, and interviews regarding health status and sociocultural aspects of life. Follow-up evaluations will occur 5 and 10 years after starting the study. Outcomes will include self-report and electrocardiogram-defined CHD, as well as measures of various social and psychological factors.


Ages Eligible for Study:   35 Years to 84 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Participant in the Jackson Heart Study
  • Diagnosis of coronary heart disease

Exclusion Criteria:

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Please refer to this study by its identifier: NCT00415415

United States, Mississippi
Jackson Heart Study
Jackson, Mississippi, United States, 39213
Sponsors and Collaborators
National Heart, Lung, and Blood Institute (NHLBI)
Principal Investigator: Herman Taylor, MD Professor of Medicine - University of Mississippi Medical Center
  More Information

Publications automatically indexed to this study by Identifier (NCT Number): Identifier: NCT00415415     History of Changes
Other Study ID Numbers: 1346
1K01HL084682-01 ( US NIH Grant/Contract Award Number )
Study First Received: December 20, 2006
Last Updated: July 28, 2016

Keywords provided by National Heart, Lung, and Blood Institute (NHLBI):
Racial Disparities
Psychosocial Risk Factors
Neighborhood Socioeconomic Status

Additional relevant MeSH terms:
Cardiovascular Diseases
Coronary Disease
Coronary Artery Disease
Myocardial Ischemia
Heart Diseases
Vascular Diseases
Arterial Occlusive Diseases processed this record on April 26, 2017