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Clinical Reminders in Test Reports to Improve Guideline Compliance

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00414401
First Posted: December 21, 2006
Last Update Posted: April 7, 2015
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
VA Office of Research and Development
  Purpose
Although beta-blockers are known to prolong survival for patients with reduced left ventricular ejection fraction, their use in the community and the VA is suboptimal.

Condition Intervention
Heart Failure, Congestive Behavioral: Clinical Reminder

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Official Title: Clinical Reminders in Test Reports to Improve Guideline Compliance

Further study details as provided by VA Office of Research and Development:

Primary Outcome Measures:
  • Prescription for any beta-blocker

Secondary Outcome Measures:
  • Prescription for carvedilol or metoprolol succinate

Estimated Enrollment: 1500
Study Start Date: May 2001
Study Completion Date: June 2006
Arms Assigned Interventions
Arm 1 Behavioral: Clinical Reminder

Detailed Description:

Background:

Although beta-blockers are known to prolong survival for patients with reduced left ventricular ejection fraction, their use in the community and the VA is suboptimal.

Objectives:

To determine if a reminder attached to the echocardiography report would increase the use of beta-blockers among patients with depressed left ventricular function.

Methods:

We are randomizing consecutive patients undergoing echocardiography at one of three VA echocardiography laboratories with reduced left ventricular ejection fraction (<40%) and no echocardiographic contraindication to beta-blockers (e.g. aortic stenosis) to a reminder for use of beta-blockers or to no reminder. The reminder gives starting doses for two commonly used beta-blockers (carvedilol and metoprolol). Patients are excluded from the analysis if they leave the health care system or die within three months of randomization. The primary outcome is a prescription for a beta-blocker between three and nine months following echocardiography

Status:

The project is complete.

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

Those undergoing echocardiography at one of the participating laboratories with an ejection fraction < 45%.

Exclusion Criteria:

aortic stenosis, mitral stenosis

  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00414401


Locations
United States, California
VA Palo Alto Health Care System, Palo Alto, CA
Palo Alto, California, United States, 94304-1290
Sponsors and Collaborators
VA Office of Research and Development
Investigators
Principal Investigator: Paul A. Heidenreich, MD MS VA Palo Alto Health Care System, Palo Alto, CA
  More Information

Publications:
Responsible Party: VA Office of Research and Development
ClinicalTrials.gov Identifier: NCT00414401     History of Changes
Other Study ID Numbers: IIR 01-108
First Submitted: December 19, 2006
First Posted: December 21, 2006
Last Update Posted: April 7, 2015
Last Verified: December 2006

Additional relevant MeSH terms:
Heart Failure
Heart Diseases
Cardiovascular Diseases